猪呼吸道疾病综合征药物防控技术研究进展

doi:10.16431/j.cnki.1671-7236.2020.03.023

Abstract

Abstract: Porcine respiratory disease complex (PRDC) is widespread in pig industry,which is the result of a combination of bacteria,viruses,parasites,bad breeding administration conditions and so on,it has caused slow growth and death of pigs so that resulted in huge economic losses.Actinobacillus pleuropneumoniae (APP),Haemophilus parasuis (Hps) and Streptococcus suis (SS) are the main bacterial pathogens,while porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus virus type 2 (PCV2) and pseudorabies virus (PRV) are common viral pathogens.Cefquinome,florfenicol and gammamycin can effectively prevent and control bacterial infections because of broad antibacterial spectrum,strong antibacterial activity and excellent pharmacokinetic characteristics in pigs,and for viral infections the commonly used drugs are cytokines and traditional Chinese medicines,especially traditional Chinese medicines,which not only can resist viruses but also enhance the body's immunity has a very broad application prospect.This article systematically expounds the antibacterial mechanism,pharmacodynamics (PD) and pharmacokinetics (PK) of the above antibacterial drugs,at the same time,the antiviral mechanism and application of the above antiviral drugs are introduced in detail.Through this review in order to provide some suggestions for the rational use of drugs to prevent and control PRDC.

Key words: porcine respiratory disease complex (PRDC); bacteria; viruses; antibacterial drugs; antiviral drugs

CLC Number:

S852.6

ZHU Minjuan, MI Kun, PU Shanju, XIE Shuyu, YUAN Zonghui, HUANG Lingli. Research Advances on Drug Prevention and Control Technology for Porcine Respiratory Disease Complex[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(3): 837-847.

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