UCP1基因变异与绵羊生长及胴体性状的关联分析

doi:10.16431/j.cnki.1671-7236.2019.11.018

Abstract

Abstract: This study was aimed to analyze the effect of UCP1 gene variation on growth and carcass traits in ovine,so as to screen out the nucleotide variation that could improve growth and carcass traits in ovine and provide materials for molecular genetic markers of important economic traits related to ovine.The mutations in intron 5 and exon 6 regions of ovine UCP1 gene were detected by PCR-SSCP in 9 ovine populations,and the relationships between mutations in growth in male and female lambs and carcass traits in male lambs were investigated using General Linear Models (GLMs) by Minitab 16.0 software.The results showed that 8 SNPs were detected in intron 5 and exon 6 regions of ovine UCP1 gene,the nucleotide substitution c.910 G/A in exon 6 resulted in amino acid change (p.Ala304Thr).The results of correlation analysis of growth traits showed that the allele in intron-5 region of ovine UCP1 gene had different effects on growth traits of male and female lambs.The presence of allele A₁ was associated with decreased birth weight in female lambs (P<0.05),and the presence of allele C₁ was associated with increased tailing weight in male lambs (P<0.05),no associations were detected between the other allele and growth traits in male and female lambs.The results of correlation analysis of carcass traits showed that the presence of allele A₁ was associated with decreased leg yield,loin yield and increased proportion of should yield (P<0.05),and the presence of allele C₁ was associated with decreased proportion of should yield (P<0.05),no associations were detected between the other allele and carcass traits in male lambs,and the genotype analysis results was consistent with allele analysis.The results indicated that the effect of ovine UCP1 gene on growth traits was gender-specific,and allele A₁ had lower carcass production traits in male lambs,which provided a theoretical basis for improving carcass production in male lambs.

Key words: UCP1 gene; gender difference; growth traits; carcass traits

CLC Number:

S813.3

AN Qingming, ZHOU Huitong, WANG Xing, WU Zhenyang, LUO Yuzhu, JON G. Hickford. Association Analysis of UCP1 Gene Variation with Growth and Carcass Traits in Ovine[J]. China Animal Husbandry and Veterinary Medicine, 2019, 46(11): 3289-3298.

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Association Analysis of UCP1 Gene Variation with Growth and Carcass Traits in Ovine

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