›› 2019, Vol. 46 ›› Issue (8): 2478-2487.doi: 10.16431/j.cnki.1671-7236.2019.08.035

• Basic Veterinary Medicine • Previous Articles     Next Articles

Research Progress on Detection Methods of Drug Residues of β-receptor Agonist

WANG Yong1, HAN Yuqi2, LU Minghua3   

  1. 1. Xinyang Center of Animal Products Quality Test and Monitoring, Xinyang 464000, China;
    2. Henan Province Center of Animal Products Quality Test and Monitoring Xuchang Branch Center, Xuchang 461000, China;
    3. Institute of Environment and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China
  • Received:2019-02-26 Online:2019-08-20 Published:2019-08-17


β-receptor agonist drugs can increase the lean rate of animals and reduce the cost of animal breeding, however, when β-agonist drugs enter the human body through the food chain, it will seriously endanger human health.Therefore, most countries in the world prohibit the illegal addition of β-receptor agonist in the breeding industry.While some offenders use β-agonist drugs for the sake of interest, and it is difficult to regulate when use β-agonist drugs in the breeding process, so it is necessary to establish fast, accurate, sensitive analytical methods to detect β-agonist drugs.At present, detection methods familiar include liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry, electrochemical method, surface enhanced Raman spectroscopy, chemiluminescence, immunoassay, etc.In the paper, the application of the agonist was briefly introduced, and the advantages and disadvantages of these methods were analyzed.In addition, the new technology for the detection of β-agonist drugs was prospected.It is foreseeable that the future development direction will be the more reliable and specific immunoassay strip analysis for on-site detection and the liquid chromatography-mass spectrometry method with the advantages of simple pretreatment method and high automation.

Key words: β-receptor agonist; drug residue; detection methods

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