早期胚胎DNA甲基化研究进展

doi:10.16431/j.cnki.1671-7236.2018.09.024

Abstract

Abstract:

DNA methylation is one of the most studied epigenetic,which plays a significant role in mediating biological progress such as gene regulation and expression,the stability of chromosome,genomic imprinting,X-chromosome inactivation.Although DNA methylation is stable,it is dynamic in the process of individual development.The function of DNA methylation modification in early embryonic developmental is not comprehensive.As the research into DNA methylation deepens,its function in pre-implantation embryos is also gradually revealed.This article mainly discusses the discovery and regulation of DNA methyltransferases (DNMTs) and the role of DNA methylation in pre-implantation embryos.

Key words: DNA methylation; pre-implantation embryos; DNA methytransferases; epigenetic

CLC Number:

Q954.4

WANG Wenjuan, YUE Yuan, AN Lei, TIAN Jianhui. Research Progress on DNA Methylation in Pre-implantation Embryo[J]. , 2018, 45(9): 2531-2536.

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Research Progress on DNA Methylation in Pre-implantation Embryo

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