›› 2017, Vol. 44 ›› Issue (4): 1239-1243.doi: 10.16431/j.cnki.1671-7236.2017.04.042

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Target Animal Safety Test of 10% Phosphoric Acid Tilmicosin Soluble Powder in Chickens

CHEN Xiao-lan1,2, TIAN Yu-zhu3, ZHANG Ming-zhu2, BU Shi-jin1,4   

  1. 1. College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China;
    2. Jiangsu Agri-animal Husbandry Vocational College, Taizhou 225300, China;
    3. QiLu Animal Health Products Co., Ltd., Jinan 250000, China;
    4. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China
  • Received:2016-08-14 Online:2017-04-20 Published:2017-05-03

Abstract:

In order to evalutate the safety of 10% phosphoric acid tilmicosin soluble powder on chickens. Forty healthy White-feathered hybrid chickens (20♂+20♀) at the age of 25 days were divided into 4 groups randomly. Each group was given tilmicosin with water at dosage of 0 mg/L,recommended dosage (75 mg/L),3 times of recommended dosage (225 mg/L) and 5 times of recommended dosage (375 mg/L) for 9d continuously. During the experiment, clinical feature,weight change and food consumption were observed,and when this experiment was ended, general pathology examination,clinical hematologic studies,blood biochemical indexes examination and physiological parameters examination were undertaken. The results showed that there were no significant influence on growth performance of chicken at the maximum dosage of 5 times of recommended dosage for 9d continuously (P>0.05), and there were no dose-dependent significant changes in physiological parameters and blood biochemical indexes. The conclusion revealed that it was very safe for chickens to use 10% phosphoric acid tilmicosin soluble powder at recommended dosage (75 mg/L).

Key words: 10% phosphoric acid tilmicosin soluble powder; chicken; safety test

CLC Number: