›› 2015, Vol. 42 ›› Issue (7): 1859-1864.doi: 10.16431/j.cnki.1671-7236.2015.07.034

Previous Articles     Next Articles

Effects of the Oral Liquid of Astragalus and Lucidum Polysaccharides on Immunological Function in Chickens Immuned with ND Vaccine

ZHOU Ze-wei1, LI Nan1, YU Zheng-rong1, ZHENG Ling-min1, LU Qian-qian1, ZHANG Yu-mei1,2   

  1. 1. College of Veterinary Medicine, Yangzhou Univercity, Yangzhou 225009, China;
    2. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China
  • Received:2014-12-23 Online:2015-07-20 Published:2015-07-23

Abstract: In order to study the effects of the oral liquid of Astragalus and Lucidum polysaccharides on immunological function in chickens,one hundred and eighty 14-day-old chickens were randomly divided into 9 groups and inoculated with the Newcastle disease vaccine.1 to 3 experimental groups were respectively the oral liquid of Astragalus and Lucidum polysaccharides high,middle and low dose groups;4 to 6 experimental groups were respectively the oral liquid of Astragalus and Lucidum polysaccharides with cyclophosphamide high,middle and low dose groups;7 to 9 experimental groups were respectively cyclophosphamide group,positive control group and saline control group.The proliferation index of spleen lymphocyte and Newcastle disease virus antibody level by HI method were determined on days 7,14,21 and 28 after vaccination.The results showed that the oral liquid of Astragalus and Lucidum polysaccharides could apparently promote lymphocyte proliferation and enhance antibody titer,and alleviate the immunosupperession of the chickens in some degree,the low dose of the oral liquid of Astragalus and Lucidum polysaccharides promoted lymphocyte proliferation best,implying that the oral liquid of Astragalus and Lucidum polysaccharides would be expected as a candidate of new-type immunopotentiator.

Key words: Astragalus and Lucidum; chicken; proliferation of spleen lymphocyte; antibody titer; immunopotentiator

CLC Number: