脂联素及其受体的研究进展及在生殖中的作用

doi:10.16431/j.cnki.1671-7236.2015.07.030

Abstract

Abstract: Adiponectin is a special protein which is secreted by adipose tissue and has many kinds of biological functions that play an important role in enhancing fatty acid oxidation,inflammation reaction and anti diabetes ect.Adiponectin mediated by AdipoR1 and AdipoR2 via AMPK,PPAR,p38MAPK signal pathway plays an important role.Adiponectin and its receptors AdipoR1 and AdipoR2 express in many tissues,AdipoR1 is mainly expressed in muscle tissue,AdipoR2 is highly expressed in liver tissue.In addition,adiponectin and its receptors also expressed in the hypothalamus,pituitary,uterus,embryo and other reproductive glands and tissues,which indicate that adiponectin plays an important role in regulating animal reproduction and embryo growth and development.

Key words: adiponectin; adiponectin receptor; expression regulation; synthesis and secretion; signal pathway; reproductive regulation

CLC Number:

R589.2

BAI Man, ZHAO Jia, ZHAN Wei, SUN Li-min, JIANG Huai-zhi. Research Progress on Adiponectin and its Receptors and their Roles in Reproduction[J]. , 2015, 42(7): 1830-1835.

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Research Progress on Adiponectin and its Receptors and their Roles in Reproduction

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