›› 2015, Vol. 42 ›› Issue (1): 234-244.doi: 10.16431/j.cnki.1671-7236.2015.01.037

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Research Progress on Vaccines of Avian Colibacillosis

MA Xing-shu   

  1. Laboratory of Molecular Biology, College of Agriculture, Hebei University of Engineering, Handan 056021, China
  • Received:2014-09-16 Online:2015-01-20 Published:2015-02-06

Abstract: Avian pathogenic Escherichia coli (APEC) is one of the most important zoonotic pathogens of a number of extra-intestinal diseases in the poultry industry, including airsacculitis, pericarditis, perihepatitis, cellulitis and septicemia. Various types of vaccine have been tested over the past few decades for control of avian colibacillosis. Unfortunately, vaccines used in poultry production make the slow progress of the researches, to date, as APECs are serotypically diverse with vaccines failing to cross-protection against heterologous challenge. Herein, we review the different categories of APEC vaccines that have been tested and provide an insight into the future of APEC vaccines.

Key words: avian colibacillosis; inactivated vaccine; attenuated vaccine; subunit vaccine; broad-spectrum vaccine; future vaccine

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