Abstract: In order to study the immunoenhancement effects of sodium houttuyfonate (SH) on chickens vaccinated with ND vaccine, 160 healthy 7-day-old non-immune chickens were randomly divided into 4 groups, namely control group and three dose groups (low-dose group, middle-dose group and high-dose group).All chickens were immunized with NDV La Sota live vaccine at day 7 for the first time, and were strengthened two weeks after that for the second time.At the same day of the second vaccination, chickens of the dose groups were respectively received oral doses of 50, 100 and 150 mg/kg SH for 7 consecutive days, chickens of control group were received equal amount of physiological saline.On days 14, 21, 28 and 35 after the first vaccination, eight chickens were randomly sampled from each group for determination of the indexes of immune organs, cytokines and antibody titers.The results showed that SH could enhance the indexes of immune organs, cytokines and antibody titers of the chickens in different degrees, especially at the dose of 100 mg/kg.

Key words: sodium houttuyfonate; immunoenhancement; chicken; Newcastle disease