中国畜牧兽医 ›› 2025, Vol. 52 ›› Issue (6): 2946-2954.doi: 10.16431/j.cnki.1671-7236.2025.06.046

• 基础兽医 • 上一篇    下一篇

鸡滑液囊支原体病研究进展

赵浩然, 马欣, 王甲, 刘博, 张一帜, 王秀丽, 姚文生, 魏津, 刘燕   

  1. 中国兽医药品监察所, 北京 100081
  • 收稿日期:2024-09-30 发布日期:2025-05-27
  • 通讯作者: 魏津, 刘燕 E-mail:447578308@qq.com;13810861788@163.com
  • 作者简介:赵浩然,E-mail:953920868@qq.com。
  • 基金资助:
    国家重点研发计划“实验动物共性关键质量评价技术标准研究”(2022YFF0711003)

Research Progress on Mycoplasma synoviae Infection in Chickens

ZHAO Haoran, MA Xin, WANG Jia, LIU Bo, ZHANG Yizhi, WANG Xiuli, YAO Wensheng, WEI Jin, LIU Yan   

  1. China Institute of Veterinary Drug Control, Beijing 100081, China
  • Received:2024-09-30 Published:2025-05-27

摘要: 鸡滑液囊支原体病是由滑液囊支原体引起的一种感染性疾病,主要表现为感染性滑膜炎、蛋壳顶端异常、气囊炎及轻度上呼吸道疾病。滑液囊支原体感染广泛存在于家禽养殖业,主要有慢性感染和隐性感染,且常与其他呼吸道病原体共同诱发混合感染,给国内养禽业造成巨大经济损失。滑液囊支原体具有多种复杂的致病机制,如黏附宿主细胞、竞争营养物质以及分泌代谢产物等。目前已有病原分离培养、分子生物学与血清学等多种检测方法可用于滑液囊支原体的实验室诊断,但国内当前可用于预防滑液囊支原体感染的疫苗种类较少,当鸡群发生感染时主要通过抗菌药物进行治疗。笔者对近年来鸡滑液囊支原体病的流行病学、临床症状、致病机制、诊断方法以及防治措施的研究进展进行综述,以期为该病的预防和控制提供新的思路。

关键词: 滑液囊支原体; 流行病学; 致病机制; 诊断; 防治

Abstract: Mycoplasma synoviae infection is an infectious disease caused by Mycoplasma synoviae,which mainly leads infectious synovitis,eggshell apex abnormality,airsacculitis and mild upper respiratory tract diseases in chickens.Mycoplasma synoviae infection is widespread in poultry industry,mainly manifested as chronic infection and recessive infection,and often co-induced mixed infection with other respiratory pathogens,causing huge economic losses to domestic poultry industry.Mycoplasma synoviae involves a variety of intricate pathogenic mechanisms,including the adhesion to host cells,competition for nutrients,and the secretion of metabolites.Currently,a variety of detection methods,including pathogen isolation and culture,molecular biology techniques,and serological testing,are available for the laboratory diagnosis of Mycoplasma synoviae.However,only a limited number of vaccines are available in China for the prevention of Mycoplasma synoviae infection.When Mycoplasma synoviae infection occurs in poultry,it is mainly treated with antibacterial drugs.The author summarized the research progress on the epidemiology,clinical symptoms,pathogenic mechanism,diagnostic methods and prevention measures of Mycoplasma synoviae infection in recent years,which provided new insights for the prevention and control of Mycoplasma synoviae infection.

Key words: Mycoplasma synoviae; epidemiology; pathogenic mechanism; diagnosis; prevention and control

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