中国畜牧兽医

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16种中药体外抗猪繁殖与呼吸综合征病毒作用的研究

冼琼珍,王丙云,伍盛鋆,黎玉莲,陈胜锋,陈志胜,计慧琴,何永明   

  1. (佛山科学技术学院动物医学系,广东佛山  528231

  • 收稿日期:2013-06-17 出版日期:2014-02-20 发布日期:2014-03-27
  • 通讯作者: 王丙云,博士,教授。
  • 作者简介:冼琼珍(1973—),女,广东人,硕士,高级实验师,研究方向:动物免疫生理与新兽药研发。
  • 基金资助:

    佛山市科技发展专项资金(2009030);佛山市禅城区科技开发专项资金(2011A1063)。

Study on Antiviral Action of 16 Kinds of Chinese Medicinal Herbs against Porcine Reproductive and Respiratory Syndrome Virus in vitro

XIAN Qiong-zhen, WANG Bing-yun, WU Sheng-yun, LI Yu-lian,CHEN Sheng-feng,CHEN Zhi-sheng,JI Hui-qin,HE Yong-ming   

  1. (Department of Veterinary Medicine,Foshan University,Foshan 528231,China)
  • Received:2013-06-17 Online:2014-02-20 Published:2014-03-27

摘要: 本试验采用对病毒的阻断、抑制、直接杀灭3种方式,研究了鱼腥草、菊花、山银花、知母、桂枝、麻黄、赤芍、柴胡、贯众、大青叶、桅子、薄荷叶、牡丹皮、水牛角、千里光、地胆草共16种中药体外抗猪繁殖与呼吸综合征病毒(PRRSV)的作用。结果表明,16种中药除了牡丹皮、千里光、大青叶外,其余13种中药均有不同程度的抗PRRSV作用,综合3种作用方式,抗PRRSV效果最好的中药是鱼腥草、菊花、知母、桂枝、赤芍,其次为麻黄、柴胡、贯众。

关键词: 猪繁殖与呼吸综合征病毒; 中药; 抗病毒

Abstract: To observe the antiviral action of 16 kinds of Chinese medicinal herbs (Houttuynia cordata Thunb,Flos Chrysanthemi,Flos Lonicerae Confusae,Anemarrhena asphodeloides,CassiaTwig,Herba Ephedrae,Radix Paeoniae Rubra,Bupleurum chinense,Dryopteris setosa,Folium Isatidis, Gardenia jasminoides Ellis,Mntha haplocalyx Briq,Paeonia suffruticosa Andr,Cornu Bubali, Herba Senecionis Scandentis,Radix Gentianae) against porcine reproductive and respiratory syndrome virus (PRRSV), the blocking, inhibiting and killing roles were detected in present study in vitro. The results showed that 13 kinds of Chinese medicinal herbs had antiviral actions against PPRSV except Paeonia suffruticosa Andr, Herba Senecionis Scandentis and Folium Isatidis, and Houttuynia cordata Thunb, Flos Chrysanthemi, Anemarrhena asphodeloides, CassiaTwig and Radix Paeoniae Rubra exhibited the best antiviral actions followed by Herba Ephedrae, Bupleurum chinense and Dryopteris setosa.

Key words: porcine reproductive and respiratory syndrome virus (PRRSV); Chinese medicinal herbs; antiviral action