›› 2014, Vol. 41 ›› Issue (12): 250-253.

• 疾病防治 • 上一篇    下一篇

细胞因子在抗鸡球虫病中的作用机制及应用的研究进展

叶丽萍, 杨文涛, 杨桂连, 王春凤   

  1. 吉林农业大学动物科学技术学院, 吉林长春 130118
  • 收稿日期:2014-06-17 出版日期:2014-12-20 发布日期:2014-12-25
  • 通讯作者: 王春凤 E-mail:wangchunfeng@jlau.edu.cn
  • 作者简介:叶丽萍(1975-),女,吉林人,硕士,实验师,研究方向:动物微生态学与动物黏膜免疫.
  • 基金资助:
    国家863计划项目(2013AA102806、2011AA10A215);国家自然科学基金项目(31272541、31272552、81170358).

Research Progress on Mechanisms of Action and Application of Cytokine against Chicken Coccidiosis

YE Li-ping, YANG Wen-tao, YANG Gui-lian, WANG Chun-feng   

  1. College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China
  • Received:2014-06-17 Online:2014-12-20 Published:2014-12-25

摘要: 鸡球虫病是一种对养禽业危害极其严重的寄生虫病,现阶段主要使用药物对该病进行防治,但长期大量使用药物产生了耐药虫株、环境污染等问题,因此球虫疫苗研制成为控制鸡球虫病的首选方法.细胞因子作为疫苗免疫佐剂能增强疫苗的特导性免疫反应,在寄生虫疫苗研究中具有重要作用.文章对细胞因子抗鸡球虫病的作用机制及其在抗球虫病中应用的研究进展作一综述.

关键词: 细胞因子; 球虫病; 作用机制

Abstract: Coccidiosis was the major parasitic disease in chickens and caused huge losses in poultry industry. The approach of anti-chicken coccidiosis was medication, but the resistance strains were emerged after mass and long term used medication, environmental pollution was severe, so anticoccidial vaccine became the first method for anti-chicken coccidiosis. Cytokines as immunoadjuvant could enhance specific immunity response of vaccine, and had a crucial role in parasite vaccine's research.This paper summarized the research progress on mechanisms of action and application of cytokine against chicken coccidiosis.

Key words: cytokine; coccidiosis; mechanisms

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