›› 2013, Vol. 40 ›› Issue (10): 224-227.

• 疾病防治 • 上一篇    下一篇

布拉酵母菌对黄曲霉毒素B1脱毒特性研究

楚杰1,3, 郭刚2, 刘金伟2, 刘可春1,3   

  1. 1. 山东省科学院生物研究所, 山东济南 250014;
    2. 山东轻工业学院, 山东济南 250353;
    3. 山东省生物传感器重点实验室, 山东济南 250014
  • 收稿日期:2013-03-20 出版日期:2013-10-20 发布日期:2013-12-19
  • 作者简介:楚杰(1965-),女,山东人,硕士,研究员,研究方向:畜牧用益生菌。
  • 基金资助:
    山东省自然科学基金(ZR2010CM054)。

Study on Detoxification of AFB1 by Saccharomyces boulardii

CHU Jie1,3, GUO Gang2, LIU Jin-wei2, LIU Ke-chun1,3   

  1. 1. Biological Research Institute of Shandong Academy of Science, Jinan 250014, China;
    2. Shandong Institute of Light Industry, Jinan 250353, China;
    3. Key Laboratory of Biosensors in Shandong Province, Jinan 250014, China
  • Received:2013-03-20 Online:2013-10-20 Published:2013-12-19

摘要: 本试验研究了不同菌体预处理、不同浓度菌体、不同作用时间、不同pH环境对布拉酵母菌脱除黄曲霉毒素B1(AFB1)效果的影响。结果发现,布拉酵母菌脱除AFB1的主要机理是吸附作用;与2 mol/L HCl 121 ℃处理30 min相比,100 ℃处理30 min更有利于布拉酵母菌对AFB1的脱毒;强酸性和偏碱性的环境也利于布拉酵母菌对AFB1的脱毒。

关键词: 布拉酵母菌; 黄曲霉毒素B1; 脱毒

Abstract: The influences on detoxification of AFB1 by Saccharomyces boulardii by different preparation methods on cells,different concentratoions of cells,different detoxification times,different pH were conducted, the mechanism of detoxification of AFB1 by Saccharomyces boulardii was absorption.Comparing with the preparations under 2 mol/L HCl and 121 ℃ for 30 min,the preparation under 100 ℃ for 30 min was more advantage on detoxification of AFB1,besides,the strong acid and weakly basic condition had a profit on detoxification of AFB1 by Saccharomyces boulardii.

Key words: Saccharomyces boulardii; AFB1; detoxification

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