›› 2013, Vol. 40 ›› Issue (1): 36-41.

• 生物技术 • 上一篇    下一篇

副猪嗜血杆菌潜在毒力因子的综述

侯娜1,2, 张培君1, 龚玉梅1, 李淑芳1, 何诚2, 贺云霞1   

  1. 1. 北京市农林科学院畜牧兽医研究所, 北京 100097;
    2. 中国农业大学动物医学院, 北京 100193
  • 收稿日期:2012-05-16 出版日期:2013-01-20 发布日期:2013-01-14
  • 通讯作者: 贺云霞(1976-),女,副研究员,博士,主要从事畜禽疫病防控研究工作。E-mail:heyunxia6@163.com;Tel:010-51503360 E-mail:heyunxia6@163.com
  • 作者简介:侯娜(1986-),女,河北人,硕士生,研究方向:实验动物学。
  • 基金资助:
    "863"国家高技术研究发展计划项目(2011AA10A210);国家自然科学基金青年基金(31001072)。

Review of Potential Virulence Factors of Haemophilus parasuis

HOU Na1,2, ZHANG Pei-jun1, GONG Yu-mei1, LI Shu-fang1, HE Cheng2, HE Yun-xia1   

  1. 1. Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China;
    2. College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
  • Received:2012-05-16 Online:2013-01-20 Published:2013-01-14

摘要: 副猪嗜血杆菌是引起猪格氏病的病原,多继发感染引起全身性疾病,其高发病率和死亡率给养殖业造成严重损失。作者主要对其潜在毒力因子,包括外膜蛋白ompP5和ompP2、自转运蛋白vtaA、转铁蛋白、6-磷酸葡萄糖酸脱氢酶和毒素等的研究作一综述,并对应用于副猪嗜血杆菌的最新研究方法进行概述,从而形成对其毒力相关研究较全面的认识。

关键词: 副猪嗜血杆菌; 潜在毒力因子; 新研究方法

Abstract: Haemophilus parasuis can cause Glasser’s disease in swine, which is mainly secondary infection and characterized by a polyserositis syndrome. An increase in the incidence, morbidity and mortality associated with Glasser’s disease has caused significant economic losses to the pig farms. By reviewing several potential virulence factors involved in H. parasuis infection and the use of new experimental approaches, the overall knowledge of the virulence related study of H. parasuis has been gained.

Key words: Haemophilus parasuis; potential virulence factors; new experimental approaches

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