›› 2010, Vol. 37 ›› Issue (7): 47-48.

• 生理生化 • 上一篇    下一篇

马蹄香镇痛作用的研究及对肠蠕动的影响

马丽娟1,2,3,李鹏1,3,宋宇1,孙远2,王珊1,刘冰2,付玉2,赵立香1,3,王永生1,王承宇2   

  1. (1.吉林大学畜牧兽医学院,长春 130062; 2.军事医学科学院军事兽医研究所,长春 130062;3.吉林农业科技学院,吉林 132101)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-07-20 发布日期:2010-07-20
  • 通讯作者: 王承宇

The Research in Analgesia and Intestine Peristalsis of Saruma Henryi Olive

MA Li-juan1,2,3,LI Peng1,3,SONG Yu1,SUN Yuan2, WANG Shan1,LIU Bing2,
FU Yu2, ZHAO Li-xiang1,3,WANG Yong-sheng1,WANG Cheng-yu2
  

  1. (1.College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China;2.Institute of Military Veterinary Medicine, Academy of Military Medical Sciences,Changchun 130062,China;3.Jilin Agricultural Science and Technology College,Jilin 132101,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-07-20 Published:2010-07-20
  • Contact: WANG Cheng-yu

摘要: 为研究马蹄香对小鼠的镇痛作用及对小鼠肠蠕动的影响,通过小鼠醋酸扭体法和小鼠热板法研究马蹄香的镇痛作用,通过小鼠碳末推进法研究马蹄香对肠蠕动的影响。在验证外周镇痛作用的扭体试验和验证中枢镇痛作用的热板试验中,马蹄香药物组和阿司匹林阳性药物组均与空白对照组存在显著差异;在碳末推进试验中,马蹄香药物组和多潘立酮阳性药物组均与空白对照组存在显著差异。结果表明,马蹄香具有外周和中枢镇痛药物活性,并能够有效促进肠蠕动。

关键词: 马蹄香; 小鼠; 镇痛; 肠蠕动

Abstract: To investigate the effects of Saruma henryi olive in analgesia and peristalsis, the pharmacological experiments were carried out by some classical methods, such as mice writhing test,mice models of hot-plate and toner test. In these experiments,the results all had significant differences.The results showed that Saruma henryi olive had the drug activity of analgesia and accelerating intestine peristalsis.

Key words: Saruma henryi olive; mice; analgesia; intestine peristalsis

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