›› 2010, Vol. 37 ›› Issue (6): 239-241.

• 经验交流 • 上一篇    

一次性使用速效止血包对小型猪止血疗效试验观察

颜克松1,战大伟1,王巍2,安宁2,王军民1   

  1. (1.解放军第一附属医院动物实验科,北京 100048;2.北京顺达佳创医学技术有限公司,北京 101300)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-06-20 发布日期:2010-06-20
  • 通讯作者: 战大伟

Hemostasis Effect of Disposable Packing Hemostasis on Miniature Pigs

YAN Ke-song1, ZHAN Da-wei1, WANG Wei2, AN Ning2, WANG Jun-min1   

  1. (1.The First Hospital Affiliated to the Chinese PLA General Hospital, Beijing 100048, China;2.Beijing Jectured Medicine Technology Co. Ltd., Beijing 101300, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-06-20 Published:2010-06-20
  • Contact: ZHAN Da-wei

摘要: 本试验旨在研究一次性使用速效止血包对动物中动脉血管损伤的止血疗效,并与速效止血粉比较止血效果。选择小型猪9只,按体重随机分为一次性使用速效止血包试验组、速效止血粉对照组、空白对照组,制作前肢肱动脉穿刺出血的小型猪中动脉失血试验模型,应用一次性使用速效止血包、速效止血粉进行止血处理,测定止血时间、创面局部最高温度及动物血压变化,取创面边缘组织,观察组织病理变化。一次性使用速效止血包与速效止血粉均能对小型猪前肢肱动脉损伤有快速止血效果,二者的止血时间无显著差异(P>0.05);速效止血粉创面止血温度高于一次性使用速效止血包温度(P<0.05),但二者都对创面及周围组织有一定程度的组织损伤。一次性使用速效止血包能对中动脉损伤引发的出血快速止血,是治疗急性出血的一种安全、有效的敷料。

关键词: 小型猪; 沸石; 止血; 敷料; 热损伤

Abstract: To study the hemostasis effect of disposable packing hemostasis on bleeding due to trauma of medium-sized artery,and compare the hemostasis effect with that of styptic powder.9 miniature pigs were divided into packing hemostasis group,styptic powder group and blank group.Establishing bleeding of forelimb medium-sized artery models on miniature pigs,haemostasis treatments were performed on individual group and parameters were measured, such as hemostatic time,regional maximum temperature and blood pressure.In addition,the tissues surrounding the haemostatic spot were picked for observation. When comparing the haemostatic effect,we found that the disposable packing hemostasis and styptic could stop bleeding quickly,and the effect of these two methods on hemostatic time has no difference;the temperature raised by styptic powder were higher than that of packing hemostasis,in addition, they all cause light tissue damage for raw surface and surrounding tissues. Disposable packing hemostasis could effectively stop bleeding caused by forelimb medium-sized artery,it could act as a secure and effective dressing for treating acute hemorrhage.

Key words: miniature pig; zeolite; hemostasis; dressing; thermal injury

中图分类号: