›› 2008, Vol. 1 ›› Issue (4): 42-45.

• 遗传繁育 • 上一篇    下一篇

解偶联蛋白及其基因多态性与能量代谢

文生萍1,张丽春2,曹振辉1,李琦华1,田允波3,柴艳1,陈宝定1,葛长荣1,贾俊静1

  

  1. 1.云南农业大学动物科学学院,昆明 650201;2.云南省红河州畜牧兽医站,蒙自 661100;3.仲恺农业技术学院生命科学学院,广州 510225
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-04-20 发布日期:2008-04-20

Uncoupling Protein and Polymorphism Regulation the Energy Metabolism

WEN Sheng-ping1, ZHANG Li-chun2, CAO Zhen-hui1, LI Qi-hua1, TIAN Yun-bo3,CHAI Yan1, CHEN Bao-ding1, GE Chang-rong1, JIA Jun-jing1
  

  1. 1. The Laboratory of Animal Nutrition and Feed Science, Yunnan Agricultural University, Kunming 650201, China;2.Honghe Animal Husbandry Institute in Yunnan Province, Mengzi 661100, China;3.College of Life Science, Guangzhou Zhongkai Agricultural and Technology College, Guangzhou 510225, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-04-20 Published:2008-04-20

摘要: 解偶联蛋白(uncoupling proteins,UCPs)是线粒体内膜蛋白质, 目前已至少发现有5种(UCP1、UCP2、UCP3、UCP4和UCP5),这个家族的蛋白质已经在人类、哺乳动物、禽类、鱼,甚至在植物的不同组织线粒体的内膜上被发现。UCPs 具有调节能量代谢, 促进脂肪酸的氧化作用,UCPs的基因多态性与脂肪代谢相关。

关键词: 解偶联蛋白; 线粒体; 基因多态性; 能量代谢

Abstract:

The uncoupling proteins are now known to be mitochondrial inner membrane proteins. Recently, more than five family members have been identified including UCP1,UCP2,UCP3,UCP4 and UCP5 in the mitochondrial inner membrane of different tissues and organs of species, such as in human, mammals, poultry, fish and even in plants. UCPs regulate the energy metabolism, increase the fatty acids oxidation and the UCPs polymorphism are related to fat metabolism. 

Key words: uncoupling proteins; mitochondria; polymorphism; energy metabolism

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