›› 2007, Vol. 34 ›› Issue (9): 74-77.

• 疾病防治 • 上一篇    下一篇

细菌耐药颉颃剂的研究现状及应用

娄飞1,李荣誉1,张龙现2   

  1. 1.郑州牧业工程高等专科学校动物医药系,郑州 450011;2.河南农业大学牧医工程学院,郑州 450002
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-09-20 发布日期:2007-09-20

Development and Application of the Antagonists to Bacterial Drug Resistance

LOU Fei1,LI Rongyu1,ZHANG Longxian2   

  1. (1.Zhengzhou College of Animal Husbandry Engineering, Zhengzhou 450011, China; 2.Henan Agricultural University, Zhengzhou 450002, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-09-20 Published:2007-09-20

摘要: 作者介绍了具有颉颃细菌耐药性作用的物质的研究应用进展情况,包括灭活酶抑制剂、药物渗透促进剂、外输泵抑制剂、细菌生物被膜抑制剂、抗菌药物增强剂、耐药质粒消除剂等。

关键词: 耐药性; 灭活酶; 外输泵; 耐药质粒; 抑制剂

Abstract: According to the mechanisms of bacterial drug resistance,many antagonists had been developed and applied,inclu-ding inhibitors of inactive enzymes,accelerators of drug permeation,inhibitors of eflux pump,inhibitors of bacterialbiofilm,synergists of antimicrobial and eliminators of resistant plasmid.

Key words: drug resistance; inactive enzymes; efflux pump; resistant plasmid; inhibitor

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