岩藻多糖的生理功能及其在动物生产中的应用

doi:10.16431/j.cnki.1671-7236.2020.08.008

摘要/Abstract

摘要： 岩藻多糖是一种天然的杂多糖，其自然资源丰富、安全无毒，具有多种生理功能：可清除体内过量自由基，激活抗氧化酶系统，抑制氧化应激通路的信号转导，发挥抗氧化功能；可通过抑制体内炎症因子的产生，抑制炎症通路，促进抗体表达，提高机体非特异性免疫等途径提高机体免疫；可通过促进癌细胞凋亡、抑制血管生成，提高机体免疫力等方式发挥抗肿瘤作用；此外，岩藻多糖还具有抑菌、抗病毒、抗血栓等多种生物学功能。动物试验表明，岩藻多糖可降低仔猪料重比，提高其对营养物质的消化率；可提高雏鸡的总采食量、总增重和饲料转化率；显著提高南亚野鲮的体重、生长速率和蛋白质功效比；提高鸡的胴体重和胸肌重量；提高猪肉抗氧化能力；降低肠道炎症和水肿；提高肠道绒毛高度，改善肠道菌群平衡；调节糖脂代谢，降低体脂含量。作者就岩藻多糖的理化性质、生理功能及其在动物生产中的应用现状进行综述，以期为岩藻多糖在动物生产中的应用提供理论依据。

关键词: 岩藻多糖; 抗氧化; 免疫; 抗肿瘤; 动物生产

Abstract: Fucoidan is a natural heteropolysaccharide,it is rich in natural resources,safe and non-toxic,it has a variety of physiological functions.Fucoidan can remove excess free radicals in the body,activate the antioxidant enzyme system,inhibit the signal transduction of oxidative stress pathways to exert antioxidant function,improve the body's immunity by inhibiting the production of inflammatory factors in the body,inhibiting the inflammatory pathway,promoting antibody expression,and improving the body's non-specific immunity,promote the apoptosis of cancer cells,and inhibit angiogenesis and improve the body's immunity to play an anti-tumor effect.Fucoidan also has various biological functions such as bacteriostasis,anti-virus and anti-thrombosis.Animal experiment shows that fucoidan can reduce the feed-to-gain ratio of piglets and improve the digestibility of nutrients,increase the total feed intake,total weight gain and feed conversion rate of chicks,increase significantly the weight,growth rate and PER of wild pheasants in South Asia,increase chicken's weight and breast muscle weight,improve the antioxidant capacity of pork,reduce intestinal inflammation and edema,increase intestinal villi height,improve intestinal flora balance,and adjust glucose and lipid metabolism,reduce body fat content.This article reviews the physical and chemical properties,physiological functions,and application status of fucoidan in animal production,in order to provide a theoretical basis for the application of fucoidan in animal production.

Key words: fucoidan; antioxidant; immunity; antitumor; animal production

中图分类号:

马玉静, 杨玲, 何荣香, 贺建华. 岩藻多糖的生理功能及其在动物生产中的应用[J]. 中国畜牧兽医, 2020, 47(8): 2404-2412.

MA Yujing, YANG Ling, HE Rongxiang, HE Jianhua. Physiological Functions of Fucoidan and Its Application in Animal Production[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(8): 2404-2412.

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