孕酮在反刍动物早期妊娠中的免疫耐受作用

doi:10.16431/j.cnki.1671-7236.2015.02.040

摘要/Abstract

摘要： 孕酮的内分泌调节与免疫功能对动物早期妊娠建立和维持十分重要。目前,在反刍动物生产中,胚胎丢失、早期流产等问题一直困扰着养殖户,而孕酮引起的免疫耐受机制还不很清楚。作者通过介绍孕酮的来源及作用方式、孕酮与机体免疫、孕酮介导妊娠免疫耐受等内容,阐述了孕酮在反刍动物早期妊娠中的免疫耐受作用,为孕酮在妊娠免疫耐受方面的研究提供理论参考。

关键词: 孕酮; 早期妊娠; 免疫耐受

Abstract: It plays an important role for the endocrine and immune function of progesterone in pregnant establishment and maintenance during early pregnancy in ruminants.At present,there is a high rate of embryonic loss and early abortion in ruminant, which plagues the farmers,while the mechanism of progesterone-induced immune tolerance is not well understood.In this review,the effect of progesterone on immune tolerance is introduced during early pregnancy in ruminants,including the source of the progesterone,mode of progesterone action,effect of progesterone on organism immunity,progesterone-mediated immune tolerance.This will provide a theory reference for the study of immune tolerance induced by progesterone during pregnancy in ruminants.

Key words: progesterone; early pregnancy; immune tolerance

中图分类号:

Q579.1⁺3

王泳翔, 杨凌, 毕江华, 李树静. 孕酮在反刍动物早期妊娠中的免疫耐受作用[J]. , 2015, 42(2): 493-497.

WANG Yong-xiang, YANG Ling, BI Jiang-hua, LI Shu-jing. Effect of Progesterone on Immune Tolerance during Early Pregnancy in Ruminant[J]. , 2015, 42(2): 493-497.

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