禽流感病毒非结构蛋白NS1在感染和免疫中的作用

Abstract

Abstract: NS1 (non-structural 1) protein is the unique non-structural protein found in avian influenza virus. It is a kind of multifunctional regulatory protein which plays a vital role in virus infection,replication and virulence. Its main function is antagonizing the host interferon and tumor necrosis factor,production inhibiting host protein synthesis as well as regulating apoptosis of infected cells. This paper reviews the latest research on the biological characteristics of NS1 protein and its role in infection and immunity which provide a reference for further research on NS1 protein’s characteristics and clinical application.

Key words: avian influenza; non-structural protein; biological characteristics

CLC Number:

S852.65⁺9.5

LU Bing;CHEN Hua-lan;BAO Hong-mei;WANG Xiu-rong;ZHANG Xiu-ying. Roles of Avian Influenza Virus Non-structural 1 Protein in Infection and Immunity[J]. , 2011, 38(5): 182-185.

[1]	LONG Feng, XIE Shouyu, CUI Pengfei, SHI Kaichuang, WEI Xiankai, FENG Shuping, QU Sujie, LU Wenjun, LI Jianfeng, YIN Yanwen, DENG Guohua. Genetic Evolutionary Dynamics Analysis of HA and NA Genes of H9 Subtype Avian Influenza Virus in Guangxi from 2016 to 2021 [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1947-1958.
[2]	XIE Shouyu, WANG Ruimin, CUI Pengfei, SHI Kaichuang, WEI Xiankai, FENG Shuping, LONG Feng, QU Sujie, LU Wenjun, HUANG Jinshan, HUANG Fengmei, WEN Xinrui, YIN Yanwen, DENG Guohua. Molecular Characteristics of Complete Genomes of Two H3 Subtype Avian Influenza Virus Isolates Derived from Sea Duck in Guangxi Province [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(4): 1319-1328.
[3]	WANG Leping, PAN Yan, TAN Yizhou, LI Lei, HAN Kaiou, CAO Yajie, LI Jun, ZHOU Yuqing, LIAO Yuying, MA Dongxin, GONG Yu, PENG Hao, WANG Xiaoye. Isolation,Identification and Genome Analysis of Escherichia coli Phage vB_EcoP_GN07 [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(4): 1522-1531.
[4]	TIAN Changqing, ZHANG Kunzhong, QI Yumei, SHI Wenjing, DONG Zhijie, ZHANG Haohao, HE Zengwen, ZHI Ji, ZHAO Xuehui, CHONG Qian, XUE Huiwen, GOU Huitian. Isolation,Identification and Biological Characteristics Analysis of a Strain of Listeria monocytogenes from Environment [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(4): 1543-1555.
[5]	CHENG Longfei, LIAO Weilian, CHEN Hongmei, JIANG Nansong, FU Qiuling, WAN Chunhe, LIU Rongchang, SHI Shaohua, HUANG Yu, FU Guanghua. Screening and Biological Characteristics of Broad-spectrum Riemerella anatipestifer Phage [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 1169-1176.
[6]	GAN Lu, ZHENG Huizhen, NUO Mingdalai, LIU Yan, JIN Min, HE Wenwen, WEN Licui, LI Yongchang, GAILIKE·Bayinchahan. Propagation of Trypanosoma evansi Yili Strain and Cloning, Expression and Bioinformatics Analysis of Its PFR Gene [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 469-478.
[7]	LIU Bin, LI Meng, XI Qianyun, SUN Jiajie, LUO Junyi, ZHANG Yongliang, CHEN Ting. Research Progress on Biological Characteristics of Hermetia illucens L. and Its Application in Poultry Production [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 586-597.
[8]	YIN Yangyan, PAN Yan, LI Xiaoning, LI Jun, LIAO Yuying, LI Changting, WEI Tianchao, PENG Hao. Study on Biological Characteristics and Antibacterial Activity in vitro of a Lactobacillus plantarum Strain [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 666-673.
[9]	LI Qi, TIAN Ye, HUANG Tao, LIU Cunxia. Research Progress of Nano-vaccine in the Prevention and Control of Avian Influenza [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 684-692.
[10]	GAO Yefan, SONG Hanan, WANG Yunan, WU Yue, NIU Ruili, ZONG Xianchun, GUAN Weijun. Study on the Isolation, Culture and Differentiation Potential of Limbal Stem Cells from Beijing You Chickens [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3372-3381.
[11]	WANG Huihui, FENG Xili, PU Feiyang, LI Yicong, WANG Mengzhu, ZHOU Xiaokai, ZHAO Zeyang, MA Zhongren, LI Zhuo, MA Xiaoxia. Prokaryotic Expression and Antigen Epitope for Non-structural Protein NS5A of BVDV Isolated from Yak [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(8): 3180-3189.
[12]	ZHOU Yuqing, MA Dongxin, WU Jie, WANG Xiaoye. Isolation,Identification and Characterization Analysis of Broad-spectrum Escherichia coli O157∶H7 CVCC4050 Phage vB_EcoM_GXBP08 [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(7): 2735-2745.
[13]	YANG Zemin, LI Shuang, JIN Zhengyu, LIAO Yixiao, YANG Ying, WEN Ming. Isolation,Identification and Biological Characteristics of a Strain of Lactobacillus plantarum from Carp [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(7): 2805-2811.
[14]	LI Jinmin, GAO Xuna, SANG Ruixin, GONG Benzhi, XU Haiyan, GU Wei, HAO Muqiang, LAN Jianghua, WANG Hong. Isolation and Evaluation of Sterilization Effect of an Avian Escherichia coli Phage [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(2): 783-190.
[15]	LI Linlin, DONG Jiawen, ZHANG Junqin, HUANG Yunzhen, SUN Minhua. Construction and Main Biological Characteristics Determination of RIA_0940 Gene Deleted Strain of Riemerella anatipestifer [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(12): 4564-4572.

Roles of Avian Influenza Virus Non-structural 1 Protein in Infection and Immunity

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments