天蚕素抗菌肽对817肉杂鸡生长性能及免疫功能的影响

doi:10.16431/j.cnki.1671-7236.2017.08.020

Abstract

Abstract:

This experiment was conducted to investigate the effects of antimicrobial peptide on growth performance and immune function of 817 broiler hybrids. Nine hundred one-day-old 817 broiler hybrids were chosen and randomly divided into 5 groups with 6 replicates per group and 30 broilers per replicate.The broilers in control group were fed with basal diet, broilers in the antibiotic group were fed with basal diet supplemented 150 mg/kg aureomycin,and that in groups Ⅰ,Ⅱ and Ⅲ were fed with basal diet supplemented 100,200 and 300 mg/kg antimicrobial peptide,respectively. The experiment period was 42 days. The results showed that average daily gain of 817 broiler hybrids in groups Ⅱ and Ⅲ was significantly increased (P<0.05),meanwhile the F/G was significantly decreased at 1-21 days old (P<0.05).The immune organ indexes of thymus,bursa of Fabricius and spleen were significantly increased at 21 and 42 days old (P<0.05),and the antibody level against ND and T lymphocyte transformation rate of 42 days old 817 broiler hybrids were improved (P<0.05). It indicated that antimicrobial peptide could increased growth performance and immune function of 817 broiler hybrids as same with aureomycin,and appropriate dosage of antimicrobial peptide was 200 mg/kg in this experiment.

Key words: 817 broiler hybrids; antimicrobial peptide; growth performance; immunity function

CLC Number:

S816.7

WANG Li, CHEN Xiao, WANG Shu-quan. Effects of Antimicrobial Peptide on Growth Performance and Immune Function of 817 Broiler Hybrids[J]. , 2017, 44(8): 2354-2359.

References

[1] 杜淑环,刘秀明,万秋,等.天蚕素抗菌肽的研究进展[J].动物营养学报,2012,24(1):41-47.
[2] 陈玉海,陈庆煌,陈科,等.抗菌肽magainin Ⅱ的密码子优化及在大肠杆菌和毕赤酵母中的表达[J].生物工程学报,2014,4:615-624.
[3] Yi T,Sun S,Huang Y,et al. Prokaryotic expression and mechanism of action of α-helical antimicrobial peptide A20L using fusion tags[J].BMC Biotechnol,2015,15(1):1-10.
[4] Zhang L, Guo D, Liu Y, et al. Probiotic Lactobacillus casei expressing porcine antimicrobial peptide PR39 elevates antibacterial activity in the gastrointestinal tract[J].Can J Microbiol,2016,7:1-9.
[5] 李波,韩文瑜.日粮中添加天蚕素抗菌肽对断奶仔猪生产性能、免疫性能及血清生化指标的影响[J].中国畜牧兽医,2014,41(7):99-102.
[6] Xiao H,Wu M M,Tan B E,et al. Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol:Ⅰ. Growth performance,immune function,and antioxidation capacity[J]. J Anim Sci,2013,91(10):4772-4780.
[7] Hu F, Gao X, She R, et al. Effects of antimicrobial peptides on growth performance and small intestinal function in broilers under chronic heat stress[J]. Poult Sci,2016, Epub ahead of print.
[8] Choi S C,Ingale S L,Kim J S,et al. An antimicrobial peptide-A3:Effects on growth performance, nutrient retention,intestinal and faecal microflora and intestinal morphology of broilers[J].Br Poult Sci,2013;54(6):738-746.
[9] Wen L F,He J G. Dose-response effects of an antimicrobial peptide,a cecropin hybrid,on growth performance, nutrient utilisation,bacterial counts in the digesta and intestinal morphology in broilers[J].Br J Nutr,2012,108(10):1756-1763.
[10] 王自蕊,谯仕彦,李波,等.饲料中添加天蚕素抗菌肽对湘云鲫生长性能、非特异性免疫功能及抗病力的影响[J].动物营养学报,2014,26(7):1856-1863.
[11] 雷岷,郭志强,任永军,等.天蚕素抗菌肽对肉兔生产性能和免疫器官指数的影响[J].中国饲料,2012,9:25-27.
[12] 李丽,王金莉.杨树花水提物和γ-氨基丁酸对817肉杂鸡的影响[J].饲料研究,2013,6:58-59.
[13] 郑明球.家畜传染病学实验指导[M].第3版.北京:中国农业出版社,2009.
[14] 黄海龙,陶淑霞,贾宇,等.抗菌肽高表达量黄粉虫对肉鸡免疫功能的影响[J].中国兽医学报,2014,34(12):2000-2004.
[15] 李波,郭强,杨利,等.饲粮中添加天蚕素抗菌肽对肉鸡生长性能的影响[J].中国家禽,2010,32(20):55-56.
[16] 姚远,匡伟,黄忠阳,等.抗菌肽天蚕素对鸡生长性能、肠道黏膜形态、盲肠菌群及免疫功能的影响[J].江苏农业学报,2014,30(2):331-338.
[17] 李金莲.抗菌肽对肉鸡免疫器官指数和新城疫疫苗免疫效果的影响[J].黑龙江省畜牧兽医,2015,11:146-147.
[18] 刘莉茹,杨开伦,滑静,等.抗菌肽对蛋用仔公鸡生长性能、免疫指标及空肠组织相关细胞因子基因mRNA表达的影响[J].动物营养学报,2012,24(7):1345-1351.
[19] 王静.抗菌肽对肉鸡生长性能和免疫功能的影响研究[D].泰安:山东农业大学,2007.
[20] 彭翔,孙全友,李杰,等.抗菌肽和姜黄素对1~21日龄肉仔鸡生长性能和免疫功能的影响[J].动物营养学报,2014,26(2):474-481.

Effects of Antimicrobial Peptide on Growth Performance and Immune Function of 817 Broiler Hybrids

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	LI Yanghui, XU Tao, ZHANG Shuxian, LIU Ke, JIA Tianqing, CHEN Ning, YIN Junliang, XI Linqiao, WANG Dong, ZHOU Xiaoling. Effect of Replacing Wheat Straw with Cumin Straw on Growth Performance, Slaughter Performance and Plasma Biochemical Parameters of Lambs [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2296-2304.
[2]	WU Liting, LU Rui, LIU Banhong, BAO Hongduo, WANG Yongjuan, ZHOU Yan, WANG Ran, ZHANG Hui. Combination of Clostridium perfringens Phage and Lactobacillus Improves Growth Performance and Regulates Intestinal Flora Function of Broilers [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2321-2332.
[3]	OUYANG Kun, WEI Limin, SUN Ruiping, XIE Yali, QI Qi, LI Xiang, LIU Quanwei, CHAO Zhe, ZHANG Yongliang, CHEN Ting. Effects of Curcumin on Growth Performance,Feed Apparent Digestibility and Serum Biochemical Indexes in Hainan Tunchang Pigs [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1867-1875.
[4]	ZHANG Huaqiang, WANG Pinsheng, LI Xiao, WEI Panpeng, YAN Lingmin, JIANG Bingbing, WANG Zhaogui, WANG Xuefang, ZENG Huanqing, FAN Yi, GAO Zhenglong, WANG Xuebing. Effects of Fermented Hybrid Broussonetia papyrifera on Growth Performance, Meat Quality,Digestive Enzyme Activity and Intestinal Flora Structure of Hu Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1876-1887.
[5]	REN Jiangang, GUAN Peng, HUANG Jianzhi, SHENG Yueyun, BAO Tiezhu, MA Zhiping, QIAN Wenxi. Effects of Dietary Energy Level on Growth-fattening Performance and Serum Biochemical Indices of Angus Bulls [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 966-976.
[6]	XIONG Taidi, JIANG Shouqun, ZHANG Huihua, ZHU Cui. Research Progress on Transportation Stress and Its Mitigation Measures in Poultry [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 977-988.
[7]	LI Bin, SHI Zhengling, ZENG Ziyou, HUANG Yingyan, LI Lin, DU Zilai, JI Yifan, WANG Di, YU Jie, MEI Shaofeng. Effects of Chicory on Growth Performance,Slaughter Traits and Meat Quality of Mahuang Broilers with Different Gender [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 500-511.
[8]	WANG Yuan, WANG Wenwen, AN Xiaoping, QI Jingwei. Effects of Dietary Fermented Soybean Meal Replacement on Growth Performance, Digestive Enzyme,and Microbita Composition in Weaned Piglets [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(1): 115-124.
[9]	LIN Xiajing, ZHENG Chuntian, XI Pengbin, CHENG Zhonggang, DING Fayuan, RUAN Dong, WANG Yibing, JIANG Shouqun. Dietary Threonine Requirement of Yellow-feathered Broilers Aged From 22 to 42 Days [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(1): 134-142.
[10]	WO Yeqianli, GAO Duo, MA Fengtao, JIN Yuhang, LIU Zhuo, SUN Peng. Effects of Two Different Organic Zinc Sources Supplementation on Growth Performance and Zinc Metabolism of Newborn Heifers [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3382-3390.
[11]	WANG Manli, TAN Zihan, WANG Shuaijie, LI Qian, ZENG Yitong, WANG Lei, ZHAO Di, ZHANG Qian, HOU Yongqing. Effects of Quercetin on Growth Performance, Blood Biochemical Indexes and Intestinal Absorption and Barrier Function in Piglets Infected with PEDV [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3411-3418.
[12]	DENG Li, LI Jie, LIU Baoguo, HANG Bolin. Molecular Design and Antimicrobial Activity Analysis of Antimicrobial Peptides Derived from Bovine Hemoglobin β-subunit [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3589-3598.
[13]	CHEN Lihong, ZHAO Mengdi, LIU Keyuan, NING Haoran, CUI Kai, LI Guangyu, SUN Weili. Study on Optimum Dietary Metabolizable Energy Level of Male Pheasants from 13 to 17 Weeks of Age [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(8): 2943-2952.
[14]	PENG Kai, CHEN Bing, ZHAO Hongxia, WANG Lijuan, ZHU Xifeng, HUANG Wen. Effects of Condensed Tannins on Growth Performance,Body Composition,Apparent Digestibility of Nutrients,and Intestinal Morphology of Lateolabtax maculatus [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(8): 2953-2960.
[15]	CHEN Xueying, WANG Huisheng, WU Jie, DENG Bo, DIAO Xinping. Effects of Dietary Bacillus licheniformis and Bacillus amyloliquefaciens on Growth Performance and Blood Indicators of Weaned Piglets [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(7): 2547-2556.