猪繁殖与呼吸综合征病毒E蛋白研究进展

Abstract

Abstract: Porcine reproductive and respiratory syndrome(PRRS)is a highly infectious disease of swine caused by porcine reproductive and respiratory syndrome virus(PRRSV). PRRS caused reproductive failure in sows,such as abortion,fetal losses, premature,parturition, mummies,stillbirths and neonatal death. E protein was encoded by ORF2b, a non-glycosylated structural protein, which size was 10 ku.It can affect viral replication, prompt the shelling of the virus particles, but do not work on the assembly of the virus, and have the ion channel protein activity. The characteristics, subcellular localization and topology,ion channel protein activity of E protein were summarized in this paper.

Key words: PRRSV; protein E; subcellular localization and topology; ion channe

CLC Number:

S852.65

TIAN Zhi-ping, XUE Jiang-dong, MA De-hui. Research Progress on Protein E of Porcine Reproductive and Respiratory Syndrome Virus[J]. , 2012, 39(10): 42-44.

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Research Progress on Protein E of Porcine Reproductive and Respiratory Syndrome Virus

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