大片形吸虫幼虫的培育及其感染小鼠的研究

Abstract

Abstract: This experiment was aimed to cultivate Fasciola gigantica metacercariae, the development process and the clinical, pathological changes of Fasciola gigantica in the intermediate host were studied. Fasciola gigantica eggs were artificially cultured and hatched. Fasciola gigantica miracidium were used to infect intermediate host, Galba pervia. The collected metacercariae were used to infect mice, the results showed that the liver had a different degree of pathological changes, and liver surface and essence contained Fascola gigantica larvae. The results indicated that Fasciola gigantica larvae could survive 7 to 8 weeks when they were raised in mice, and could cause regular pathological changes and even death. So we could use the mouse as experimental animal of Fasciola hepatica infection for the study of early diagnosis, immune prevention, treatment and other aspects of Fasciola hepatica disease.

Key words: Fasciola gigantica; Galba pervia; miracidium; metacercariae; mice

CLC Number:

S852.7

LI Xue, HUANG Tian, ZHU Bing-lun, WU Wen-de, WEI Zhi-peng, ZHAO Ming-long, XU Xin-ting, CHEN Han-zhong. Study on Cultivation of Fasciola gigantica Metacercariae and its Infection in Mice[J]. , 2014, 41(12): 244-250.

References

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Study on Cultivation of Fasciola gigantica Metacercariae and its Infection in Mice

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