›› 2014, Vol. 41 ›› Issue (11): 275-278.

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Allergic Study of Ivermectin Microemulsion

XING Shou-ye1,2, ZHOU Xu-zheng1, LI Bing1, NIU Jian-rong1, WEI Xiao-juan1, ZHANG Ji-yu1   

  1. 1.Key Laboratory of New Animal Drug Discovery, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730070, China;
    2. College of Veterinary Medicine, Gausu Agricultural University, Lanzhou 730050, China
  • Received:2014-06-27 Online:2014-11-20 Published:2014-12-06

Abstract: The study was aimed to observe the allergic reaction of ivermectin microemulsion injection on animals. Active systemic allergy test and passive cutaneous anaphylaxis test were carried out to study the allergic reaction of ivermectin microemulsion injection on Wistar rat and guinea pig, respectively, according to . The results showed that the allergic reaction of ivermectin microemulsion injection on Wistar rat and guinea pig were both negative. The study provided experiment evidences for the safety evaluation of ivermectin microemulsion.

Key words: ivermectin microemulsion; guinea pig; rat; allergic test

CLC Number: