益气健脾中药对腹泻仔猪小肠黏膜组织结构的影响

Abstract

Abstract: To investigate the effect of Tonifying Qi-Nourishing Spleen herbs on small intestinal mucosa in diarrheal piglets, antibiotics and Chinese herbal medicine were adopted to heal diarrheal piglets. Piglets were sacrificed by bloodletting in veins, dissected peritoneal cavity, and gathered small intestinal mucosa abacterially. Then, the changes of histopathology and cellular structures in small intestinal mucosa were observed by using pathological and electron microscopic sections. The results showed that small intestinal mucosa had no obvious pathological changes except slight hemorrhage in Chinese herbal medicine group. Nevertheless, there were more pathological changes in antibiotics group, for instance, small intestinal mucosa had desquamated with extensive hyperemia and hemorrhage concomitantly; epithelial cells were degenerated and necrotic;eosinophilic granulocyte displayed cellular infiltration, which included inflammatory cell infiltrate principally as lymphocyte;microvillus had desquamated and arranged indiscriminately; mucous membrane cells were damaged seriously and mitochondria presented structural abnormalities. We concluded that the therapy of using antibiotics in diarrheal piglets might cause pathological changes and functional impairment in small intestinal mucosa, and using Chinese herbal medicine might be beneficial for plerosis of small intestinal mucosa, which would provide the theoretical foundation to cure diarrhea and improve growth performance of piglets.

Key words: Chinese herbal medicine; piglet; small intestinal mucosa; pathological change; electron microscope observation

CLC Number:

S853.7

ZHAO Juan, BAI Yuan-sheng, WU Guo-tao, ZHANG Dong-ling, WANG Shu-hua, YANG Zhong, REN Jie, MENG Dong-xia, MENG Fan, LIU Yi-fei. Effect of Tonifying Qi-Nourishing Spleen Herbs on Small Intestinal Mucosa in Diarrheal Piglets[J]. , 2014, 41(11): 252-257.

References

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Effect of Tonifying Qi-Nourishing Spleen Herbs on Small Intestinal Mucosa in Diarrheal Piglets

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