H5N1亚型禽流感病毒疫苗的研究现状及应用前景

Abstract

Abstract: The H5N1 subtype avian influenza virus (AIV) had been known as a pathogen with specialties of the strongest infection, the highest mortality and the widest epidemic. H5N1 subtype AIV was endemic in many countries around the world and had caused considerable economic losses to the poultry industry. However, owing to no effective treatment measures, vaccine inoculation had become the most-effective prevention measure and the key loop. Therefore,the development of the safe, high-efficiency and low-cost vaccine was one of the current hotspots for the control of avian influenza. Based on the large numbers of research achievements of avian influenza vaccine, we comprehensively described the research status of avian influenza vaccine from the following aspects,the virus inactivated vaccine, attenuated live vaccine, genetic engineering vaccine and other technology application etc. Moreover, we summarized the difficulties and drawbacks of studies and gave the future prospects of vaccine application with the purpose of providing a comprehensive background and reference for the control of avian influenza.

Key words: H5N1 subtype avian influenza virus; vaccine; research status; prospect

CLC Number:

FENG Shu-ying, DONG Shi-zhen, ZHANG Shu-xiao. Research Status and Application Prospects of H5N1 Subtype Avian Influenza Virus Vaccines[J]. , 2013, 40(9): 208-213.

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Research Status and Application Prospects of H5N1 Subtype Avian Influenza Virus Vaccines

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