半胱氨酸天冬氨酸特异性蛋白酶介导的细胞凋亡对精子发生发育及冷冻保存的影响

Abstract

Abstract: Caspase is a family of cysteine proteases that play an important role in regulating apoptosis. Spermatogenesis and development involve an early waves of germ cell apoptosis, which are required for maintaining the balance between germ cell proliferation and death, to ensure sufficient number and quality of well differentiation and mature spermatozoa. Main reasons probably owe to structural damage, functional lost of boar spermatozoa and apoptosis during cryopreservation, which finally lead to sperm program cell death, apoptosis. The present paper reviewed the influence mechanism of apoptosis mediated by caspase, which showed tightly relationship between apoptosis mediated by caspase and spermatozoa cryopreservation, spermatogenesis and development.

Key words: Caspase; apoptosis; spermatogenesis and development; cryopreservation

CLC Number:

Q813

DING Li, ZENG Chang-jun. Influences on Apoptosis Mediated by Caspases on Spermatogenesis, Development and Cryopreservation[J]. China Animal Husbandry & Veterinary Medicine, 2013, 40(4): 138-144.

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Influences on Apoptosis Mediated by Caspases on Spermatogenesis, Development and Cryopreservation

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