黄芪杂多糖对仔猪IL-6和PR-39表达的影响

Abstract

Abstract: To study the effects of astragalus heteropolysaccharides (AHPS) on the expression of IL-6 and PR-39 of piglets, the proliferation activities of T lymphocytes and monocytes in peripheral blood were determined by MTT, the IL-6 contents in serum were detected by ELISA, the expression levels of PR-39 in marrow were analyzed by RT-qPCR. The results showed that AHPS could promote the proliferation activities of T lymphocytes and monocytes in peripheral blood.IL-6 contents in serum showed dose-dependent patterns at the same time, and increased significantly with the extension of the injection time.AHPS could increased the level of PR-39 mRNA and showed the dose-dependent patterns. According to the relevant literature and the results, we inferred that AHPS might improve the immunity of piglets by increasing the content of IL-6 and the expression level of PR-39.

Key words: astragalus heteropolysaccharides; T lymphocytes; monocytes; IL-6; PR-39

CLC Number:

S853.7

FAN Kuo-hai, LI Juan-juan, ZHANG Bei, LI Hong-quan. Effects of Astragalus Heteropolysaccharides on the Expression of IL-6 and PR-39 of Piglets[J]. , 2013, 40(2): 1-5.

References

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Effects of Astragalus Heteropolysaccharides on the Expression of IL-6 and PR-39 of Piglets

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