蛋白酪氨酸磷酸酶Shp2基因mRNA在小鼠睾丸发育过程中的表达

Abstract

Abstract: In this study, we analyzed the expressional pattern of Shp2 gene on the transcriptional level in mice testicles in different developmental stages. General RT-PCR and Real-time PCR were uesd to investigate the Shp2 expression in 16 groups of postnatal mice according to the differently developmental stages. The result showed that the temporal expression of Shp2 gene in mice testicles presented successively regardless of the daily growth according to the general RT-PCR assay. The result of Real-time PCR showed that, during the period from twentieth day to thirty-first day, the expression quantity of Shp2 gene fluctuated from the extremly significantly increase (P<0.01) to extremly significantly decrease (P<0.01) to extremly significantly increase again (P<0.01), and finally, the amount was back to normal gradually after the thirty-first day (P>0.05).The results indicated that Shp2 involved in the development of mouse testis, but the functions in details needed to be explored and investigated in depth.

Key words: development of testicle; mouse; Shp2 gene; pattern of expression

CLC Number:

Q786

CAI Xiao-li, GENG Guo-xia, LIU Ya-wei, LI Qing-wang. Expression of Protein Tyrosine Phosphatase Shp2 Gene mRNA in Development of Mouse Testicle[J]. , 2013, 40(11): 143-147.

References

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Expression of Protein Tyrosine Phosphatase Shp2 Gene mRNA in Development of Mouse Testicle

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