›› 2013, Vol. 40 ›› Issue (1): 25-28.

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Recent Research Advances in Target Cell of Porcine Circovirus Type 2 and its Cell Receptor

LI Peng1,2, WANG Li-ping1, ZHU Yan-ping1, WANG Xuan-nian1,2, ZHANG Gai-ping2   

  1. 1. Biotechnology Research Center, Department of Life Science and Technology, Xinxiang University, Xinxiang 453003, China;
    2. Henan Provincial Key Laboratory of Animal Immunology, Key Laboratory of Animal Immunology, Ministry of Agriculture, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China
  • Received:2012-06-25 Online:2013-01-20 Published:2013-01-14

Abstract: Porcine circovirus type 2 (PCV2) is the primary causative agent of several syndromes collectively known as porcine circovirus-associated disease (PCVAD). However, the role of ligand epitope and cell receptor in pathogenesis of PCV2 is still uncertain.Receptor recognition is the first step in viral entry, and plays an important role in viral infectivity and pathogenesis.This paper reviews the current knowledge relating to interactions between PCV2 and its target cell surface receptors.

Key words: porcine circovirus type 2; target cell; cellular receptor

CLC Number: