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Research of Dynamics of Viremia and Antibody Responses of Yellow Chicken Infected by Avian Leukosis Virus Subgroup J

WANG Xiao-fen, LIU Xue-mei, LIAO Ya-lin, WU Xiao-chan, LIAO Ming, CAO Wei-sheng   

  1. Key Laboratory of Animal Disease Control and Prevention,Ministry of Agriculture, College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China
  • Received:2012-02-23 Online:2012-08-20 Published:2012-08-24

Abstract: The dynamics of viremia,ALV-J antibody response in yellow chickens and p27 antigen shedding in cloacal swabs were examined respectively after the 11-day-old yellow chicken embryos were inoculated with hemangioma related ALV-J SCAU-HN06 isolate via allantoic cavity. The results showed that viremia could be detected as early as 1 week post hatch,there was a viremia peak at 7 week,and the positive rate of viremia remained more than 80% continuously since 9 week. ALV-J antibody response could be detected as early as 6 week by ELISA,the positive rate of antibody was no more than 33.3% during the trial. The positive rate of p27 antigen in cloacal shedding rised quickly,reached peak at 3 week,then kept at high level. The study suggested that ALV-J isolate infection via egg inoculation could result in persistent viremia and immunotolerance. The study provided the basis for ALV-J control and eradication in yellow chickens.

Key words: subgroup J avian leukosis virus(ALV-J); yellow chicken; viremia; dynamic

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