Mx基因的抗病毒研究进展

›› 2012, Vol. 39 ›› Issue (5): 173-175.

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Advance in the Antiviral Research of Mx Gene

XIN Ting-ting^1,2, WANG Hong-mei¹, HE Hong-bin¹

1. Dairy Cattle Research Center, Shandong Academy of Agricultural Sciences, Jinan 250100, China;2. College of Life Science, Northeast Agricultural University, Harbin 150030, China

Received:2011-11-03 Revised:1900-01-01 Online:2012-05-20 Published:2012-05-20

Abstract

Abstract: The human myxovirus resistance(Mx) protein is a GTPase and a key mediator of the interferon-induced antiviral response against a wide range of viruses, and can inhibit the replication of a wide range of negative-and positive-strand RNA viruses as well as DNA viruses. Here we briefly review the most salient features of Mx genes and protein in the structure and antiviral function, and prospects development of antiviral transgenic animal breeding using this gene.

Key words: Mx gene; antiviral; antiviral mechanism

CLC Number:

Q78

XIN Ting-ting;WANG Hong-mei;HE Hong-bin. Advance in the Antiviral Research of Mx Gene[J]. , 2012, 39(5): 173-175.

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Advance in the Antiviral Research of Mx Gene

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