DNA甲基转移酶抑制剂在动物体细胞核移植研究中的应用

Abstract

Abstract: Methylation plays an important regulatory role in embryo development and organization. Somatic nuclear transfer embryos often show the abnormal mode of DNA methylation, DNA methyltransferase inhibitors can inhibit the levels of DNA methylation, so as to improve the efficiency of SCNT.The application of DNA methyltransferase inhibitors in animal somatic cell nuclear transfer was taken an overview in this paper.

Key words: DNA methylation; DNA methyltransferase inhibitors; somatic cell nuclear transfer

CLC Number:

Q345⁺.21

MENG Li-na, LUO Ting, KE Hao, LIU Xiao-hua, SUN Hong-liang, LU Feng-hua, SHI De-shun. Application of DNA Methyltransferase Inhibitors in Animal Somatic Cell Nuclear Transfer Research[J]. , 2012, 39(12): 133-136.

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Application of DNA Methyltransferase Inhibitors in Animal Somatic Cell Nuclear Transfer Research

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