Abstract: To improve the economic profit from the goat husbandry, as well as to benefit research fields such as medicine, pharmacology, animal sciences including stem cell research that require large amount of goats for experimental studies, we must improve the reproductivity and the multifetal pregnancy (MP) rate. Thus, we carefully desired a study using cloprostenol for synchronizating the reproductive cycles of Jiangsu Haimen goats originated in East China area to improve the utilization of goats through improving multifetal pregnancy rate. The two experimental groups each included 136 from cloprostenol induced (T) and untreated (UT) goats resulted in a MP rate of 78.7% (107/136) and 39.0% (53/136), respectively. The average fetus per pregnant goat improved from 1.31 of uninduced (UT) to 2.01 for the induction group (T). The improvement was statistically significant (P<0.01). Noteworthy, the new born goats resulted from the induction group developed normally. The present study demonstrated that cloprostenol could significantly improve rate of multifetal preganancy and thus goat production, with important economical benefit and research applications in the agricultural, medical and scientific fields.

Key words: goats; cloprostenol; multi-fetal rate; stem cells