EB病毒膜抗原的表达与IL-6和TNF-α水平相关性研究

›› 2011, Vol. 38 ›› Issue (8): 225-227.

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Research about the Relation between the Expression of Epstein-Barr Virus Membrane Antigen and the Levels of IL-6 and TNF-α

KANG Ai-jun¹, GUO Chang-zhan², TIAN Feng¹, ZHENG Zhen-hui¹

1. Department of Laboratory Animal Science, Peking University Health Science Center, Beijing 100191, China;2. Department of Immunology,School of Basic Medical Sciences,Peking University Health Science Center,Beijing 100191,China

Received:2010-12-23 Revised:1900-01-01 Online:2011-08-20 Published:2011-08-20

Abstract

Abstract: To study the relation between the expression of EBV membrane antigen (MA) and the levels of IL-6 and TNF-α. Taking the KM mouse as the control group, ELISA was applied to observe the level of IL-6 and TNF-α in the mouse. The level of IL-6 in the EBV mice increase compared to the KM mice. The level of TNF-α in the EBV mice went up significantly compared to the KM mice. We proved that expression of EBV membrane antigen (MA) could promote expression of IL-6 and TNF-α.

Key words: Epatein-Barr virus membrane antigen(MA); BLLF1 transgenic mouse; IL-6; TNF-α

CLC Number:

R392

KANG Ai-jun;GUO Chang-zhan;TIAN Feng;ZHENG Zhen-hui. Research about the Relation between the Expression of Epstein-Barr Virus Membrane Antigen and the Levels of IL-6 and TNF-α[J]. , 2011, 38(8): 225-227.

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Research about the Relation between the Expression of Epstein-Barr Virus Membrane Antigen and the Levels of IL-6 and TNF-α

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