Abstract: Twenty mice infected with Aspiculuris tetraptera naturally were assigned randomly into four groups (n=5). GroupsⅠ-Ⅲ were fed with Nitazoxanide at a dosage of 200, 400, 800 mg/kg every 24 hours for 5 consecutive days, group Ⅳ with no treatment were used as the control. Faecal egg count reduction percentage and crude insecticide rate were used as the evaluation of drug effects of insecticide targets. The results showed that the insecticide effect of Nitazoxanide on Aspiculuris tetraptera increased with the increase of drug dose, and the dose of 800 mg/kg had the best effect.

Key words: Nitazoxanide; Aspiculuris tetraptera; mice