玉米赤霉烯酮对小鼠胸腺上皮细胞线粒体的影响

Abstract

Abstract: The purpose of the present study was to investigate in vitro cytotoxicity of Zearalenone(ZEN) on thymic epithelial cells in mice. MTT assay, mitochondria activity analysis, mitochondria membrane potential and flow cytometry were used to study the effects of ZEN on thymic epithelial cells in vitro in Kunming mice aged 1 month. The results of this study showed that:higher doses(10 to 25 μg/mL) ZEN could enhance significantly mitochondria metabolism competent to MTT of thymic epithelial cells, could enhance mitochondria activity, could advance mitochondria membrane potential.

Key words: Zearaleone; mitochondrion; thymic epithelial cells; mice

CLC Number:

S852.4⁺4

FAN Xiao-long;XU Li-na;YAN Hai-kuo;DENG Xian-bo;XU Qi-wen;LIANG Zi-sen;MA Yong-jiang. Effects of ZEN on Mitochondrion of Thymic Epithelial Cells in Mice[J]. , 2011, 38(6): 41-45.

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Effects of ZEN on Mitochondrion of Thymic Epithelial Cells in Mice

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