金黄色葡萄球菌诱发建立乳房炎小鼠病理模型

Abstract

Abstract: 30 Kunming mice were divided into 3 groups random to establish the mouse mastitis patho-model. 30 mice were injected separately with 50 μL sterile physiological saline，1.0×10⁵ CFU/mL and 2.0×10⁵ CFU/mL Staphylococcus aureus in the forth lacteal gland. The appearance of lacteal gland and the diversity of histological section were observed. The results indicated that the mice 24 h after being injected with bacterium appeared evident clinical symptoms; the different degree inflammation was found in the lacteal gland; plenty of neutrophilic granulocyte infiltrated in the acinar lumina and the compartment became widen were discovered by the method of histopathology. The result indicated that the mouse mastitis model was established by the Staphylococcus aureus.

Key words: mouse; Staphylococcus aureus; mastitis; patho-model

CLC Number:

S857.2⁺6

TAN Bing-hai; ZHANG Gui-lin;CAO Rong-feng. The Establishment of Mouse Mastitis Patho-model Induced by Staphylococcus aureus[J]. , 2010, 37(3): 158-159.

[1]	HE Xingli, WANG Zhaoyuan, ZHOU Peiyao, MOU Quanzhou, SHEN Binglei. Research Progress on Immune Escape Mechanism of Staphylococcus aureus in Dairy Cow Mastitis [J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(2): 748-758.
[2]	HOU Zhiming, ZHANG Lei, HE Yibo, ZHANG Junpeng, ZHANG Shuyi. Research Progress of Omics Techniques in the Field of Subclinical Mastitis in Dairy Cows [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(9): 3510-3518.
[3]	WANG Chao, GONG Zhiguo, LIU Xinyu, ZHAO Jiamin, YANG Xiaolin, WANG Yu, YU Zhuoya, BAI Yunjie, CAO Jinshan, LIU Bo, ZHANG Shuangyi, MAO Wei, GAO Ruifeng. Exploring of the Mechanism of Traditional Chinese Medicine Compounds in Preventing and Treating Dairy Cows Mastitis Based on Network Pharmacology and Molecular Docking [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(9): 3842-3852.
[4]	BAI Yunfei, ZHAO Tingting, LI Wenlong, XING Yue, REN Xiaoli, GUO Gang, YU Ying. Verification and Application of Dairy Cow Mastitis Risk Assessment System in Pastures in North and South of China [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(8): 3267-3274.
[5]	FAN Yimeng, WEI Yuanyuan, WANG Huiru, GA yu, ZHANG Yannan, ZHAO Qingyu, HAO Zhihui. Potential Mechanisms of Chinese Veterinary Medicine Compound Rukang Granules in the Treatment of Dairy Cow Mastitis Based on Network Pharmacology and Molecular Docking Technology [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2507-2517.
[6]	GUO Yaru, LI Kexin, WANG Li, LIU Jinyu, SHI Lei, REN Youshe. Effects of Selenium on Lead-Induced Apoptosis of Mouse Leydig Cells in vitro [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(4): 1404-1411.
[7]	ZHONG Huachen, WANG Lifang, GUO Chenyang, LIU Jialin, SONG Jie. Isolation,Identification and Drug Resistance Analysis of Pathogenic Bacteria from Milk Samples and Environment of Mastitis in Inner Mongolia [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 817-826.
[8]	GAO Ying, YU Yongtao, MA Yun, MA Zhengbing, YUAN Shuangjie, CUI Shengwei. Comparative Analysis of Diversity of Milk Microbiota in Cows with Mastitis and Healthy Cows [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(12): 5043-5055.
[9]	DANG Ruiying, CHANG Junshuai, LIANG Yan, QU Yonggang, LI Yanfang, CHENG Lulu, LIU Ruotong, YANG Shengyuan, WANG Ziyang, ZHANG Xiaoyu, ZHAO Yu, ZHOU Haiqin, XIE Fangde. Isolation and Characterization of Staphylococcus aureus Phage P82 from Dairy Mastitis [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(6): 2318-2325.
[10]	QIU Shulei, CHEN Xiaolan, YANG Haifeng, CHEN Yuku, HU Yuanliang, GAO Yongxu, WU Caihong. Effects of Selenized Garlic Polysaccharide on the Function of Mouse Peritoneal Macrophages [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(3): 1144-1152.
[11]	JIAO Anhui, ZHANG Xiaomeng, ZHAO Yuhan, WANG Yu, GAO Qingshan. Effects of Limonin on in vitro Maturation of Mouse Oocytes and Embryo Development of in vitro Fertilization [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(10): 3891-3900.
[12]	ZHANG Pengju, FU Liyun, CHEN Zhiqiang, SHANG Jingxue, ZHANG Yuanda, CAI Xiaoli, ZHAN Wen. Study on the Effect of Gongyingqiaolu Powder in Treating Subclinical Cow Mastitis [J]. China Animal Husbandry and Veterinary Medicine, 2021, 48(3): 1027-1033.
[13]	ZHANG Qingjuan, MA Xuanxuan, TENG Da, YANG Na, WANG Xiumin, MAO Ruoyu, HAO Ya, SHAN Yuxue, LIU He, FAN Huan, WANG Jianhua. Study on Antibacterial Effect of Antimicrobial Peptide NZ2114 Against Streptococcus dysgalactiae Isolated from Bovine Mastitis [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(8): 2603-2614.
[14]	LI Haiqiang, YANG Dasheng, LU Qi, TANG Shaoxun. Comparison of Two Methods for Detecting Recessive Mastitis in Cows [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(8): 2677-2683.
[15]	SHAN Yuxue, YANG Na, TENG Da, WANG Xiumin, MAO Ruoyu, HAO Ya, MA Xuanxuan, FAN Huan, WANG Jianhua. The Disinfection Effect of Antimicrobial Peptide NZ2114 on Streptococcus agalactiae Isolated from Bovine Mastitis and Its Biofilm [J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(7): 2284-2294.

The Establishment of Mouse Mastitis Patho-model Induced by Staphylococcus aureus

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments