Abstract: With the scale enlargement of livestock breeding and rapid development of feed industry，in recent years，house-flies larva and its extractive were investigated extensively，such as house-flies larva hydrolysis，grease，chitosan and antibacterial peptide. House-flies larva contains many kinds of fatty acid，mineral，vitamin，amino acid and metabolizable energy. In addition，some deep investigations such as the physical and chemical property，application，and medical value of the extracting peptide，grease and chitosan from house-flies larva have become new research areas in the 21st century. Research has shown that these extractives were useful to regulate the nutrition metabolism，improve production performance of livestock and poultry. The author reviewed the application and research advancement of house-flies larva in animal production，in order to provide theoretical and practical basis for conserving protein feed，develop new kinds of safe antibacterials and feed additives.

Key words: house-flies larva; hydrolysis; grease; chitosan; antibacterial peptide