›› 2009, Vol. 36 ›› Issue (7): 178-180.

• 疾病防治 • Previous Articles     Next Articles

Chicken IFN-γ Gene Cloning and Expression and the Study Progress of Anti-coccidia Effect of IFN-γ

LEI Na, CHEN Shu-ming   

  1. (College of Aimal Science and Technology, Shanxi Agricultural University, Taigu 030801, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-07-20 Published:2009-07-20
  • Contact: CHEN Shu-ming

Abstract: Chicken interferon comes from the activated T cells, NK cells.It has many functions, such as broad-spectrum anti-viral, anti-tumor and the role of immunity regulation.Chicken interferon-γ gene has been cloned successfully in vero cells and E. coli and so on.Also chicken interferon-γ gene has been expressed and proved to enhance the immunity function against chicken coccidiosis.It could activate macrophages and reinforce the role of anti-infective of K cells, NK cells.In addition, ChIFN-γ can be used as immunoenhancer, which has a wide range of application.

Key words: chicken; interferon-γ; gene expression; coccidiosis

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