硫酸软骨素对大鼠心肌膜微血管内皮细胞分泌IFN-γ的影响

China Animal Husbandry & Veterinary Medicine ›› 2009, Vol. 36 ›› Issue (6): 42-44.

• 生理生化 • Previous Articles Next Articles

Effects of Chondroitin Sulfate on IFN-γ Release of Rat Myocardial Microvascular Endothelial Cells in vitro

XU Ju^1，2，ZHANG Tao²，LV Juan²，TIAN Li-fang³，HU Ge²， MU Xiang²，JIANG Wen-can¹

(1.College of Animal Medicine, Sichuan Agricultural University, Yaan 625014, China;2.Beijing Key Laboratory of Traditional Chinese Veterinary Medicine, Beijing University of Agriculture,Beijing 102206, China; 3.Baoding Vocational Technology College, Baoding 071057, China)

Received:1900-01-01 Revised:1900-01-01 Online:2009-06-20 Published:2009-06-20

Abstract

Abstract: To study whether chondroitin sulfate （CS） could induce rat myocardial microvascular endothelial cells (RMMVECs) in vitro to secrete IFN-γ. Using double antibody sandwich ELISA to detect the level of IFN-γ produced by RMMVECs stimulated with CS in cell supernatant liquid.The level of IFN-γ produced by RMMVECs stimulated with CS in cell supernatant liquid was increased dramatically, and got the maximum at 24 h. CS could induce rat microvascular endothelial cells to secrete IFN-γ.

Key words: IFN-γ; chondroitin sulfate; microvascular endothelial cells; rat

CLC Number:

S853.74

XU Ju;ZHANG Tao;LV Juan;TIAN Li-fang;HU Ge;MU Xiang;JIANG Wen-can. Effects of Chondroitin Sulfate on IFN-γ Release of Rat Myocardial Microvascular Endothelial Cells in vitro [J]. China Animal Husbandry & Veterinary Medicine, 2009, 36(6): 42-44.

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Effects of Chondroitin Sulfate on IFN-γ Release of Rat Myocardial Microvascular Endothelial Cells in vitro

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