Abstract: An individual pig-farm in southeast Guizhou prefecture，a group of sows were transferred to a simple pigsty that warehouse into a converted pigsty to feed，as the hot weather, the pigsty was poorly ventilated，dark and damp，it had poor sewage on the ground, all filthy pig, resulting 10 sows were ill，the clinical symptoms of sick sows mainly concentrated local swelling and the thick kind of sticky secretions outflow from vaginal．In order to identified pathogens, the sick sows pus and vaginal secretions was used to smear examination, and then carried out the separation of bacteria and bacterial culture, biochemical tests were done，finally，it was diagnosed as Staphylococcus aureus disease of sow, sick sows have been cured by using ampicillin and erythromycin combined with surgery.

Key words: sows; Staphylococcus aureus disease; diagnosis and treatment