Abstract: Foot-and-mouth disease (FMD) is caused by foot-and-mouth disease virus and infect cloven-hoofed animals. It is suffering from acute, fever, sexually transmitted diseases contact. Vaccination is still an effective measure to prevent and control FMD. The main foot-and-mouth vaccines are attenuated vaccines, inactivated vaccines and new vaccines. Since the 1980s, genetic engineering subunit vaccines, synthetic peptide vaccines, vaccine vectors, gene deletion vaccines and recombinant vaccine epitopes, the DNA vaccine and other new types of vaccine research has become increasingly active. The progress of types of vaccine are reviewed.

Key words: foot-and-mouth disease; traditional vaccines; new types of vaccine