Abstract: Salbutamol (SAL) is a selective beta stimulant that can reduce animal fat deposition and improve carcass lean meat percentage, but the accumulation of SAL in animal products can cause food poisoning, a serious threat to human health.Since 2002, SAL has been listed as a prohibited drug in the aquaculture industry in China, but there are still frequent reports of poisoning caused by SAL residue in pork, so it is of great significance to detect the residue of SAL in animal-derived food.In recent years, with the emergence of new materials and the rapid development of laboratory detection technology, the detection methods of SAL residue have made progress in terms of sensitivity, specificity and detection efficiency.The author reviewed the progress of SAL detection technology in recent years, including chromatography, immunology analysis, surface enhanced Raman spectroscopy, sensor analysis, electrospray extraction ionization mass spectrometry, etc., in order to provide help for rapid and accurate detection of SAL residue in large-scale aquaculture industry.

Key words: salbutamol; residue detection; β-agonist; animal derived food