›› 2019, Vol. 46 ›› Issue (7): 2183-2192.doi: 10.16431/j.cnki.1671-7236.2019.07.037

• Products Quality and Safety • Previous Articles    

Research Advance on Detection Methods of Antibacterial Residues in Animal Food

LIU Dingxi, YANG Jiecheng, ZHOU Hongchao, GUO Kangkang   

  1. College of Veterinary Medicine, Northwest A & F University, Yangling 712100, China
  • Received:2019-01-07 Online:2019-07-20 Published:2019-07-22


Antibacterial drugs have played an important role in the prevention and treatment of animal diseases.However,non-standard and over-dose drug use and even abuse have made the antibacterial drug residues in animal foods increasingly prominent,causing widespread concern.The detection of antimicrobial drug residues is an important part for animal foods safety.According to the purpose and needs of the detection,it can be divided into on-site testing and laboratory testing.Colloidal gold immunechromatography is the most widely used on-site detection method.In addition,there are many laboratory detection methods,which can be divided into qualitative detection methods and quantitative detection methods for antibacterial drug residues.The former mainly includes 2,3,5-triphenyltetrazolium chloride method (TTC method), paper method (PD method) and activity detection method,etc.The latter mainly includes high performance liquid chromatography,liquid chromatography-mass spectrometry,ultra-performance liquid chromatography-mass spectrometry,capillary electrophoresis,biosensor and immunoassay,etc.These techbiques can meet the needs of different testing purposes and experimental conditions.In this article,the authors summarized the on-site detection and laboratory detection techniques of antibacterial residues in meat,eggs and milk which could lay a solid foundation to further study the rapid,sensitive,high-throughput and low-cost detection of antimicrobial drug residues in food.

Key words: animal derived food; antibacterial drugs; residue; detection method; food safety

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