脂肪酸对动物骨骼肌的代谢调控作用

doi:10.16431/j.cnki.1671-7236.2017.03.018

Abstract

Abstract:

Fatty acids are thought to supply energy for cell traditionally. Recent studies have shown the effect of fatty acids on cellular growth, development and metabolism. Skeletal muscle is an important place for fatty acids consumption, and it's also the main target where fatty acids play its role. Palmitic acid is closely related to skeletal muscle insulin resistance (IR); Oleic acid can increase skeletal muscle fatty acids oxidation and triglyceride synthesis through peroxisome proliferator activated receptor;Linolenic acid relieves skeletal muscle insulin resistance by increasing glucose utilization; Conjugated linoleic acid (CLA) influences skeletal muscle metabolism via multiple signal passways;Docosahexaenoic acid (DHA) and arachidonic acid (ARA) can significantly change myosine heavy chain gene expression;Eicosapntemacnioc acid (EPA) has some effect on skeletal muscle glucose metabolism,mitochondrial action and Apelin system.This review focuses on the effects of different fatty acids on skeletal muscle.And we will have a better understanding about the diverse regulatory mechanism of various fatty acids, and we also hope that this paper will provide some theoretical foundations for the research and development of fatty acids products.

Key words: fatty acid; skeletal muscle; insulin; mitochondrial

CLC Number:

Q547

WANG Le-shan, ZUO Xu-dong, JIANG Qing-yan, WANG Li-na. The Metabolic Regulatory Effect of Fatty Acids on Mammal Skeletal Muscle[J]. , 2017, 44(3): 748-754.

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The Metabolic Regulatory Effect of Fatty Acids on Mammal Skeletal Muscle

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