毛发皮质醇激素作为慢性应激评定指标的研究进展

doi:10.16431/j.cnki.1671-7236.2015.09.029

Abstract

Abstract: Making hair cortisol as the gold standard of reflecting chronic stress level is prospective and innovative.Hair cortisol not only can be used in detecting and estimating the chronic stress level of animals, but also can be benefit for understanding the body's physiological and pathological process and making effective health management strategy in time.Blood, saliva, urine and milk cortisol concentrations can be regarded as matrices for reflecting acute stress level as well, they have been used in detecting and establishing the diurnal profile of circulating cortisol studying.But hair which is a good supplementary matric can reflect the chronic stress level retrospectively.Hair cortisol as a reflection of the biochemical markers of chronic stress has the advantages of no invasive, relatively sensitive detection and convenient sampling stress, and hair cortisol is a heritable trait (h²=0.31).The utility of hair cortisol as a maker for HPA activity, and a useful tool for identifying genetic variation influences on long term individual differences in HPA activity.This article summarized the relationship between the cortisol and animal's healthy, the regulating mechanism and genetic adaptation change under chronic stress and the research progress of evaluation indicators during chronic stress, the research progress of hair as a matric of cortisol, the limitations and challenge of regarding hair cortisol as the biochemical marker to reflect the chronic stress level in the future.

Key words: chronic stress; hair cortisol; detection analysis; limitations; challenge

CLC Number:

DOU Jin-huan, LI Zhong-shu, XU Qing, WANG Ya-chun. Research Progress on Hair Cortisol as Evaluation Indicators of Chronic Stress[J]. , 2015, 42(9): 2405-2410.

References

[1] Kumar A,Mehrotra S,Singh G,et al.Sustained delivery of exogenous melatonin influences biomarkers of oxidative stress and total antioxidant capacity in summer-stressed anestrous water buffalo (Bubalus bubalis)[J].Theriogenology,2014,31:1-6.

[2] Tiwari R V,Parajuli P,Sylvester P W.γ-tocotrienol-induced endoplasmic reticulum stress and autophagy act concurrently to promote breast cancer cell death[J].Biochem Cell Biol,2015,93:1-15.

[3] Bouazza A,Bitam A,Amiali M,et al.Effect of fruit vinegars on liver damage and oxidative stress in high-fat-fed rats[J].Pharm Biol,2015,8:1-6.

[4] St-Pierre N R,Cobanov B,Schnitkey G.Economic losses from heat stress by US livestock industries[J].Journal of Dairy Science,2003,86:52-77.

[5] Yang Y,Wang Y,Zhang J,et al.System responses to chronic cold stress probed via H-NMR spectroscopy in plasma and urine matrices[J].Mol Biosyst,2015,23:1-10.

[6] Indo H P,Yen H C,Nakanishi I,et al.A mitochondrial superoxide theory for oxidative stress diseases and aging[J].J Clin Biochem Nutr,2015,56(1):1-7.

[7] Kido T,Dao T V,Ho M D,et al.High cortisol and cortisone levels are associated with breast milk dioxin concentrations in Vietnamese women[J].Eur J Endocrinol,2014,170(1):131-139.

[8] Tiganescu A,Walker E A,Hardy R S,et al.Localization,age- and site-dependent expression,and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in skin[J].J Invest Dermatol,2011,131(1):30-36.

[9] Hall D L,Lattie E G,Antoni M H,et al.Stress management skills,cortisol awakening response,and post-exertional malaise in chronic fatigue syndrome[J].Psychoneuroendocrinology,2014,49:26-31.

[10] Lei J,田雯.激素对乳腺上皮细胞亮氨酸代谢的调控作用[J].中国畜牧兽医,2014,41(2):138.

[11] Ali S,Jabeen S,Alam F.Multimodal approach to identifying malingered posttraumatic stress disorder:A review[J].Innov Clin Neurosci,2015,12(1-2):12-20.

[12] Steinheuser V,Ackermann K,Schonfeld P,et al.Stress and the city:Impact of urban upbringing on the (re)activity of the hypothalamus-pituitary-adrenal axis[J].Psychosom Med,2014,76(9):678-685.

[13] Queitsch C,Sangster T A,Lindquist S.Hsp90 as a capacitor of phenotypic variation[J].Nature,2002,417(6889):618-624.

[14] Chow K C.Hsp70 (DnaK)——An evolution facilitator[J].Trends Genet,2000,16(11):484-485.

[15] Dikmen S,Alava E,Pontes E,et al.Differences in thermoregulatory ability between slick-haired and wild-type lactating Holstein cows in response to acute heat stress[J].J Dairy Sci,2008,91(9):3395-3402.

[16] Olson T A,Lucena C,Chase C J,et al.Evidence of a major gene influencing hair length and heat tolerance in Bos taurus cattle[J].J Anim Sci,2003,81(1):80-90.

[17] Kassahn K S,Crozier R H,Portner H O,et al.Animal performance and stress:Responses and tolerance limits at different levels of biological organisation[J].Biol Rev Camb Philos Soc,2009,84(2):277-292.

[18] Goldstein D S.Clinical assessment of sympathetic responses to stress[J].Ann N Y Acad Sci,1995,771:570-593.

[19] Lee D Y,Kim E,Choi M H.Technical and clinical aspects of cortisol as a biochemical marker of chronic stress[J].BMB Rep,2015,6:209.

[20] Gaillard Y,Vayssette F,Balland A,et al.Gas chromatographic-tandem mass spectrometric determination of anabolic steroids and their esters in hair.Application in doping control and meat quality control[J].J Chromatogr B Biomed Sci Appl,1999,735(2):189-205.

[21] Wennig R.Potential problems with the interpretation of hair analysis results[J].Forensic Sci Int,2000,107(1-3):5-12.

[22] Koren L,Mokady O,Karaskov T,et al.A novel method using hair for determining hormonal levels in wildlife[J].Animal Behaviour,2002,63(2):403-406.

[23] del Rosario González-de-la M R,Vara R A V,Lemus-Ramirez V,et al.Effects of adrenocorticotropic hormone challenge and age on hair cortisol concentrations in dairy cattle[J].Can J Vet Res,2011,75(3):216-221.

[24] Cooper G A,Kronstrand R,Kintz P.Society of hair testing guidelines for drug testing in hair[J].Forensic Sci Int,2012,218(1-3):20-24.

[25] Li J,Xie Q,Gao W,et al.Time course of cortisol loss in hair segments under immersion in hot water[J].Clin Chim Acta,2012,413(3-4):434-440.

[26] Davenport M D,Tiefenbacher S,Lutz C K,et al.Analysis of endogenous cortisol concentrations in the hair of rhesus macaques[J].Gen Comp Endocrinol,2006,147(3):255-261.

[27] Thomson S,Koren G,Fraser L A,et al.Hair analysis provides a historical record of cortisol levels in Cushing's syndrome[J].Exp Clin Endocrinol Diabetes,2010,118(2):133-138.

[28] Noppe G,de Rijke Y B,Dorst K,et al.LC-MS/MS based method for long-term steroid profiling in human scalp hair[J].Clin Endocrinol,2015,Epub ahead of print.

[29] Russell E,Kirschbaum C,Laudenslager M L,et al.Toward standardization of hair cortisol measurement:Results of the first international interlaboratory round robin[J].Ther Drug Monit,2015,37(1):71-75.

[30] Sauve B,Koren G,Walsh G,et al.Measurement of cortisol in human hair as a biomarker of systemic exposure[J].Clin Invest Med,2007,30(5):E183-E191.

[31] Desai G S,Mathews S T.Saliva as a non-invasive diagnostic tool for inflammation and insulin-resistance[J].World J Diabetes,2014,5(6):730-738.

[32] Hernandez C E,Thierfelder T,Svennersten-Sjaunja K,et al.Time lag between peak concentrations of plasma and salivary cortisol following a stressful procedure in dairy cattle[J].Acta Vet Scand,2014,56:61.

[33] Fukasawa M,Tsukada H,Kosako T,et al.Effect of lactation stage,season and parity on milk cortisol concentration in Holstein cows[J].Livestock Science,2008,113(2-3):280-284.

[34] Fukasawa M,Tsukada H.Relationship between milk cortisol concentration and the behavioral characteristics of postpartum cows introduced to a new group[J].Animal Science Journal,2010,81(5):612-617.

[35] Gow R,Thomson S,Rieder M,et al.An assessment of cortisol analysis in hair and its clinical applications[J].Forensic Sci Int,2010,196(1-3):32-37.

[36] Smy L,Shaw K,Smith A,et al.Hair cortisol as a novel biomarker of HPA suppression by inhaled corticosteroids in children[J].Pediatr Res,2015,Epub ahead of print.

[37] Boumba V A,Ziavrou K S,Vougiouklakis T.Hair as a biological indicator of drug use,drug abuse or chronic exposure to environmental toxicants[J].Int J Toxicol,2006,25(3):143-163.

[38] Antonella C,Ghislaine R B F,Stefano M,et al.Determination of cortisol in hair as indicator of long-term stress in Simmental dairy cows[J].Reproduction in Domestic Animals,2005,40(5):396.

[39] Kirschbaum C,Tietze A,Skoluda N,et al.Hair as a retrospective calendar of cortisol production-increased cortisol incorporation into hair in the third trimester of pregnancy[J].Psychoneuroendocrinology,2009,34(1):32-37.

[40] Gao W,Xie Q,Jin J,et al.HPLC-FLU detection of cortisol distribution in human hair[J].Clin Biochem,2010,43(7-8):677-682.

[41] Fairbanks L A,Jorgensen M J,Bailey J N,et al.Heritability and genetic correlation of hair cortisol in vervet monkeys in low and higher stress environments[J].Psychoneuroendocrinology,2011,36(8):1201-1208.

Research Progress on Hair Cortisol as Evaluation Indicators of Chronic Stress

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