一定纯度中药复方多糖对鸡细胞免疫和体液免疫的影响

doi:10.16431/j.cnki.1671-7236.2015.04.026

Abstract

Abstract: In order to select the best dose of certain purified Chinese herbal medicinal compound polysaccharide (cCHMPS), which had been proven to significantly affect the immunity of mice, three hundred one-day-old male Liangfeng Green-feet Ma chickens were randomly divided into six groups, namely control group, levamisole hydrochloride (LM) group, Astragalus polysaccharide (APS) group, high, medium and low-dose purified cCHMPS group, and with 50 chickens for each group. Eight-day-old chickens were vaccined with physiologic saline, LM, APS, high, medium and low-dose purified cCHMPS, once a day for 7 consecutive days. On days 8, 14, 21, 28, 35 and 42 after the first vaccination, 5 chickens' blood for each group were sampled for determination of T, B lymphocyte proliferation activities and NDV antibody levels. The results showed that APS and purified cCHMPS at different doses could significantly or extremely significantly promote the proliferation of peripheral T, B lymphocytes (P<0.05;P<0.01), increase the concentrations of NDV antibody, enhance cellular immunity and humoral immunity, and the medium-dose purified cCHMPS was the best.

Key words: certain purified Chinese herbal medicinal compound polysaccharide; Astragalus polysaccharide; levamisole hydrochloride; cellular immunity; humoral immunity

CLC Number:

S852.5

SHANG Yun-xia, ZHU Xiao-qing, GU Xin-li, LI Xiao-zhen, QIAO Hai-bo, JIA Shu-hong, ZHANG Dong-sheng. Effects of Certain Purified Chinese Herbal Medicinal Compound Polysaccharide on Cellular Immunity and Humoral Immunity in Chicken[J]. , 2015, 42(4): 943-949.

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Effects of Certain Purified Chinese Herbal Medicinal Compound Polysaccharide on Cellular Immunity and Humoral Immunity in Chicken

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