›› 2011, Vol. 38 ›› Issue (8): 177-181.

• 疾病防治 • 上一篇    下一篇

蓝舌病病原分子生物学及免疫学研究进展

王荣亮1,2, 胡骑2, 信爱国2   

  1. 1. 云南农业大学动物科技学院,云南昆明 650201;2. 云南省畜牧兽医科学院 云南省热带亚热带动物病毒重点实验室,云南昆明 650224
  • 收稿日期:2010-12-15 修回日期:1900-01-01 出版日期:2011-08-20 发布日期:2011-08-20
  • 通讯作者: 信爱国

Progress on Pathogen Molecular Biology and Immunology of Bluetongue

WANG Rong-liang1,2, HU Qi2, XIN Ai-guo2   

  1. 1. College of Aninal Science and Technology,Yunnan Agricultural University,Kunming 650201,China;2. Yunnan Tropical and Subtropical Animal Virus Disease Laboratory,Yunnan Animal Science and Veterinary Institute,Kunming 650224,China
  • Received:2010-12-15 Revised:1900-01-01 Online:2011-08-20 Published:2011-08-20

摘要: 蓝舌病病毒通过吸血昆虫(库蠓)在易感反刍动物之间叮咬进行传播。在家畜中,蓝舌病易发于某些品种的羊,具有典型症状,呈地方性流行;牛感染蓝舌病通常不表现出临床症状。作者分析和总结了近年蓝舌病疫情发生和传播可能的潜在路线,病毒分子生物学研究概况,致病机理及宿主对蓝舌病病毒的免疫反应,并对蓝舌病疫苗的研究进展作了介绍,建议要加强对该病的深入研究,防患于未然。

关键词: 蓝舌病病毒; 流行情况; 病原分子生物学; 免疫学

Abstract: Bluetongue virus (BTV) is transmitted from infected to susceptible ruminants by hematophagous vector midges (Culicoides species).Amongst domestic livestock,bluetongue is most common in certain breeds of sheep. BTV infection of sheep with clinical symptom is typical in enzootic regions. BTV infection of cattle are most common,whereas asymptomatic. This review analysed and summarized the BTV epidemic situation and potential spread of disease transimission line,as well as the progress on the molecular biology and pathogensis of BTV and the host immune response against BTV. Furthermore,the advances on vaccine of BTV were descirbed,and also suggested to enhance the study of BTV for provention BTV in the future.

Key words: bluetongue virus(BTV); epidemic situation; pathogen molecular biology; immunology

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